Pulmonary Evaluation of Post-COVID-19 Patients: An Ecuadorian Experience.

Autor:	Cherrez-Ojeda I; Universidad Espíritu Santo, Samborondón, Ecuador.; Respiralab, Respiralab Research Group, Guayaquil, Ecuador., Sanchez-Angarita E; Centro de Investigación Respiratoria (CIR), Guayaquil, Ecuador., Vanegas E; Universidad Espíritu Santo, Samborondón, Ecuador.; Respiralab, Respiralab Research Group, Guayaquil, Ecuador., Farfán Bajaña MJ; Universidad Espíritu Santo, Samborondón, Ecuador.; Respiralab, Respiralab Research Group, Guayaquil, Ecuador., Robles-Velasco K; Universidad Espíritu Santo, Samborondón, Ecuador.; Respiralab, Respiralab Research Group, Guayaquil, Ecuador., Osorio MF; Universidad Espíritu Santo, Samborondón, Ecuador.; Respiralab, Respiralab Research Group, Guayaquil, Ecuador., Sarfraz A; Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Sarfraz Z; Research & Publications, Fatima Jinnah Medical University, Lahore, Pakistan., Calderón JC; Respiralab, Respiralab Research Group, Guayaquil, Ecuador.; Médico Residente de Neumología, Hospital Universitario Fundación Favaloro, Ciudad Autónoma de Buenos Aires, Argentina.; Docente, Departamento de Medicina Universidad Favaloro, Ciudad Autónoma de Buenos Aires, Argentina., Cáneva J; Jefe de Neumología, Hospital Universitario Fundación Favaloro, Ciudad Autónoma de Buenos Aires, Argentina.; Titular de Medicina, Universidad Favaloro, Ciudad Autónoma de Buenos Aires, Argentina.; Máster Internacional en Hipertensión Pulmonar, Sociedad Española de Cardiología, Spain., Gochicoa-Rangel L; Departamento de Fisiología Respiratoria, Instituto Nacional de Enfermedades Respiratorias, 'Ismael Cosío Villegas', Ciudad de México, Mexico., Lascano MP; Respiralab, Respiralab Research Group, Guayaquil, Ecuador., Fernández Cadena JC; Omics Sciences Laboratory, Universidad Espíritu Santo, Samborondón, Ecuador., Andrade Molina DM; Omics Sciences Laboratory, Universidad Espíritu Santo, Samborondón, Ecuador., Freire AX; University of Tennessee Health Science Center, Tennessee, United States., Felix M; Universidad Espíritu Santo, Samborondón, Ecuador.; Respiralab, Respiralab Research Group, Guayaquil, Ecuador.
Jazyk:	angličtina
Zdroj:	Journal of community hospital internal medicine perspectives [J Community Hosp Intern Med Perspect] 2022 Apr 12; Vol. 12 (2), pp. 30-34. Date of Electronic Publication: 2022 Apr 12 (Print Publication: 2022).
DOI:	10.55729/2000-9666.1031
Abstrakt:	Background: Despite the growing concerns related to the potential of long-term pulmonary sequelae due to COVID-19, data about intermediate and long-term changes in the respiratory function of patients who recover is relatively sparse, particularly in developing countries. Objectives: To assess the characteristics and pulmonary function at follow-up in a sample of Ecuadorian patients that recovered from the virus. Methods: We conducted a cross-sectional study that included 43 patients after symptomatic COVID infection, who were evaluated by spirometry, single breath DLCO, and 6MWT. For statistical analysis we performed point biserial correlations, and chi squared tests. Results: Overall, 30.3% of patients (n = 13) reported persistent symptoms, with fatigue being the most common (23.3%, n = 10). Around 34.9% (n = 15) of the sample had a restrictive spirometry pattern, 18.6% (n = 8) had an abnormally decreased adjusted DLCO. A restrictive spirometry pattern was associated with an abnormally low adjusted DLCO (χ 2 (2) = 11,979, p = 0.001). Conclusion: We found that a considerable proportion of patients presented with persistent symptoms and alterations in pulmonary function following COVID-19, mainly a restrictive respiratory pattern and abnormally low DLCO. Further studies are needed to determine which patients may benefit from the follow-up with specific pulmonary function tests. Competing Interests: Declaration of competing interest The authors report there are no competing interests to declare in relation to this work. (© 2022 Greater Baltimore Medical Center.)
Databáze:	MEDLINE
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