[Correction of Partial Volume Effect Using CT Images in Brain 18 F-FDG PET].

Autor: Onoue F; Graduate School of Health Sciences, Kumamoto University., Yamamoto S; Uozumi Clinic., Uozumi H; Uozumi Clinic., Kamezaki R; Division of Radiology, Department of Medical Technology, Kumamoto University Hospital., Nakamura Y; Division of Radiology, Department of Medical Technology, Kumamoto University Hospital., Ikeda R; Division of Radiology, Department of Medical Technology, Kumamoto University Hospital., Shiraishi S; Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University., Tomiguchi S; Japanese Red Cross Society Kumamoto Health Care Center., Sakamoto F; Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University.; Department of Medical Radiation Sciences, Faculty of Life Sciences, Kumamoto University.
Jazyk: japonština
Zdroj: Nihon Hoshasen Gijutsu Gakkai zasshi [Nihon Hoshasen Gijutsu Gakkai Zasshi] 2022 Jul 20; Vol. 78 (7), pp. 741-749. Date of Electronic Publication: 2022 Jun 16.
DOI: 10.6009/jjrt.2022-1260
Abstrakt: Purpose: We performed partial volume effect correction of PET images using 18 F-FDG-PET and CT images taken consecutively, compared it with correction using MRI images, and investigated the usefulness of correction using CT images.
Methods: A total of 9 clinically normal subjects were included in the study, and the CT and MRI images of each subject were segmented and normalized. PET images were coregistered to each morphological image and then normalized. The normalized morphological images of each subject were used to mask the brain atlas and to correct for the partial volume effect. For each brain region, comparison of counts, two-group test between CT- and MRI-corrected groups, and correlation analysis were performed.
Results: As a result of correction, some error was observed between the two groups. Correlation analysis showed strong positive correlations in many areas, but weak correlations were found in some areas. In the region where significant differences were found, the two groups showed strong positive correlation, and in the region where weak correlation was found, the error tended to be small.
Conclusion: It is suggested that the correction by CT can be performed with the same accuracy, although some errors are generated compared with MRI.
Databáze: MEDLINE