Comparison of Serum Adropin Levels in Patients with Diabetes Mellitus, COVID-19, and COVID-19 with Diabetes Mellitus.

Autor: Aydın P; Department of Anesthesiology and Reanimation, Erzurum Regional Training and Research Hospital, Erzurum, Turkey., Uzunçakmak SK; Department of Health Services, Bayburt University Vocational School, Bayburt, Turkey., Tör İH; Department of Anesthesiology and Reanimation, Erzurum Regional Training and Research Hospital, Erzurum, Turkey., Bilen A; Department of Internal Medicine, Atatürk University Faculty of Medicine, Erzurum, Turkey., Özden A; Department of Pediatric Endocrinology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.
Jazyk: angličtina
Zdroj: The Eurasian journal of medicine [Eurasian J Med] 2022 Jun; Vol. 54 (2), pp. 197-201.
DOI: 10.5152/eurasianjmed.2022.22128
Abstrakt: Objective: In the present study, the relationship between a poor prognosis and adropin levels in diabetic patients with coronavirus disease 2019 was investigated by measuring serum adropin levels and levels of D-dimer, C-reactive protein, and ferritin, which are considered prognostic factors for coronavirus disease 2019.
Materials and Methods: Hundred volunteer participants treated in the Erzurum Regional Training and Research Hospital were included in this study. Serum adropin levels were measured by enzyme-linked immunosorbent assay. The relationship between serum adropin level and C-reactive protein, ferritin, and D-dimer levels was analyzed by correlation analysis.
Results: The participants' serum adropin levels differed between the groups (P = .0007). The control group had the highest adropin levels among groups. The lowest adropin levels were in the COVID + diabetes mel- litus group. Adropin levels of diabetes mellitus, COVID, and diabetes mellitus+COVID groups were sig- nificantly decreased when compared to the control (P < .05). There was a significant negative correlation between adropin and C-reactive protein, D-dimer, and ferritin.
Conclusion: Adropin can be used as an auxiliary biomarker, a prognostic factor in the early management of coronavirus disease 2019 patients with diabetes mellitus. We think that our study will guide future studies conducted in this field.
Databáze: MEDLINE
Externí odkaz: