Progressive Global Ataxia With Sensory Changes as a Paraneoplastic Syndrome in a Patient With Chromophobe Renal Cell Carcinoma.
| Autor: | Basree MM; Internal Medicine, OhioHealth Riverside Methodist Hospital, Columbus, USA., Rudy R; Internal Medicine, University of Pikeville - Kentucky College of Osteopathic Medicine, Pikeville, USA., Romaniello C; Internal Medicine, OhioHealth Riverside Methodist Hospital, Columbus, USA., Smith DE; Neurology, OhioHealth Riverside Methodist Hospital, Columbus, USA., Kander E; Hematology/Oncology, Columbus Oncology Associates, Columbus, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 May 11; Vol. 14 (5), pp. e24913. Date of Electronic Publication: 2022 May 11 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.24913 |
| Abstrakt: | Paraneoplastic syndromes (PNS) are rare and can be challenging to diagnose and treat. The uniqueness of PNS lies in the complexity of presentation, the importance of early diagnosis, and the role of multidisciplinary care in managing those patients to mitigate long-term neurologic complications. We describe a patient with metastatic renal cell carcinoma who presented with a complex constellation of neurological symptoms (progressive global ataxia and sensory changes) that did not resolve following nephrectomy. While complete resolution of symptoms was not achieved, he did have stabilization of his neurologic decline with the initiation of cancer-directed therapies. Competing Interests: The authors have declared financial relationships, which are detailed in the next section. (Copyright © 2022, Basree et al.) |
| Databáze: | MEDLINE |
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