Sudden Vasopressin Withdrawal Causing Transient Central Diabetes Insipidus: A Case Report.
| Autor: | Pata R; Pulmonary and Critical Care Medicine, One Brooklyn Health, New York, USA.; Pulmonary and Critical Care Medicine, University of Cincinnati Medical Center, Cincinatti, USA., Nway N; Internal Medicine, Interfaith Medical Center, New York, USA., Logvinsky IK; Medicine, American University of Antigua, New York, USA., Lutaya I; Medicine, American University of Antigua, New York, USA., Chowdhury T; Internal Medicine, One Brooklyn Health System, New York, USA. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 May 13; Vol. 14 (5), pp. e24966. Date of Electronic Publication: 2022 May 13 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.24966 |
| Abstrakt: | Vasopressin is a peptide hormone produced by the hypothalamus and stored in the posterior pituitary. It is secreted in response to hypotension and hyperosmolarity. Vasopressin and its analogs have been widely used in vasodilatory shocks such as septic shock and cardiogenic shock. The sudden withdrawal of vasopressin after its prolonged use can lead to polyuria and rising sodium levels, which is concerning for the diagnosis of diabetic insipidus (DI); likely central rather than nephrogenic in origin. We present a case of diabetic insipidus following the sudden discontinuation of a prolonged vasopressin infusion for septic shock, which responded to tapering doses of desmopressin. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Pata et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|