Ozonized 2-hydroxypropyl-β-cyclodextrins as novel materials with oxidative and bactericidal properties.

Autor: Haddad E; Laboratoire de Génie Chimique, Université de Toulouse, CNRS, INPT, UPS, 4 Allée Emile Monso, 31432 Toulouse, France; Physiologie, Pathologie et Génétique Végétales (PPGV), Université de Toulouse, INP-PURPAN, 75 Voie du Toec, 31076 Toulouse, France., Pagès M; Plateforme TOAsT, Université de Toulouse, INP-PURPAN, 75 Voie du Toec, 31076 Toulouse, France; Physiologie, Pathologie et Génétique Végétales (PPGV), Université de Toulouse, INP-PURPAN, 75 Voie du Toec, 31076 Toulouse, France., Violleau F; Plateforme TOAsT, Université de Toulouse, INP-PURPAN, 75 Voie du Toec, 31076 Toulouse, France; Laboratoire de Chimie Agro-industrielle, LCA, Université de Toulouse, INRA, 4 Allée Emile Monso, 31000 Toulouse, France., Marsan O; Centre Interuniversitaire de Recherche et d'Ingénierie des Matériaux, 4 Allée Emile Monso, 31432 Toulouse, France., Manero MH; Laboratoire de Génie Chimique, Université de Toulouse, CNRS, INPT, UPS, 4 Allée Emile Monso, 31432 Toulouse, France., Richard R; Laboratoire de Génie Chimique, Université de Toulouse, CNRS, INPT, UPS, 4 Allée Emile Monso, 31432 Toulouse, France., Torré JP; Laboratoire de Génie Chimique, Université de Toulouse, CNRS, INPT, UPS, 4 Allée Emile Monso, 31432 Toulouse, France. Electronic address: jean-philippe.torre@ensiacet.fr.
Jazyk: angličtina
Zdroj: Carbohydrate polymers [Carbohydr Polym] 2022 Sep 01; Vol. 291, pp. 119516. Date of Electronic Publication: 2022 Apr 23.
DOI: 10.1016/j.carbpol.2022.119516
Abstrakt: Ozonized (2-Hydroxypropyl)-β-cyclodextrins (Oz-HPbCDs) were produced by direct gas/solid reaction between gaseous ozone (O 3 ) and solid HPbCD. The solid materials obtained were first characterized using physical and chemical methods and compared to the initial HPbCD. The main process parameters of the synthesis were studied independently to assess their effect on the oxidizing power of Oz-HPbCDs. The ability of the Oz-HPbCDs to retain their oxidative properties over time was evaluated, at different storage temperatures, for a period of at least two months. Lastly, aqueous solutions of HPbCD and Oz-HPbCD at different concentrations were contacted with bacterial strains of Escherichia coli and Streptococcus uberis to see whether these materials might have bactericidal properties. Since normal bacterial growth was noted with HPbCD, the antimicrobial efficiency of Oz-HPbCDs was clearly demonstrated on these two types of bacteria.
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Databáze: MEDLINE
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