Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery.
| Autor: | Kataoka M; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Gomi K; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Ichioka K; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Iguchi T; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Shirota T; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Makino A; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Shimada K; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Maruyama K; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Mihara M; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan., Kajikawa S; Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Annals of coloproctology [Ann Coloproctol] 2023 Aug; Vol. 39 (4), pp. 315-325. Date of Electronic Publication: 2022 Jun 13. |
| DOI: | 10.3393/ac.2022.00234.0033 |
| Abstrakt: | Purpose: C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC). Methods: Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching. Results: The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed. Conclusion: In patients with CRC, CAR of POD 7 was a significant prognostic factor. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|