| Autor: |
Hardison RL; Battelle Memorial Institute, Columbus, Ohio., Nelson SW; Battelle Memorial Institute, Columbus, Ohio., Barriga D; Battelle Memorial Institute, Columbus, Ohio., Feliciano Ruiz N; Battelle Memorial Institute, Columbus, Ohio., Ghere JM; Battelle Memorial Institute, Columbus, Ohio., Fenton GA; Battelle Memorial Institute, Columbus, Ohio., Lindstrom DJ; Battelle Memorial Institute, Columbus, Ohio., James RR; Battelle Memorial Institute, Columbus, Ohio., Stewart MJ; U.S. EPA, Durham, North Carolina., Lee SD; U.S. EPA, Durham, North Carolina., Calfee MW; U.S. EPA, Durham, North Carolina., Ryan SP; U.S. EPA, Durham, North Carolina., Howard MW; Battelle Memorial Institute, Columbus, Ohio. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of occupational and environmental hygiene [J Occup Environ Hyg] 2022 Aug; Vol. 19 (8), pp. 455-468. Date of Electronic Publication: 2022 Jun 28. |
| DOI: |
10.1080/15459624.2022.2088768 |
| Abstrakt: |
The list of EPA-approved disinfectants for coronavirus features many products for use on hard, non-porous materials. There are significantly fewer products registered for use on porous materials. Further, many common, high-touch surfaces fall in between non-porous materials such as glass and porous materials such as soft fabrics. The objective of this study was to assess the efficacy of selected commercially available disinfectant products against coronaviruses on common, high-touch surfaces. Four disinfectants (Clorox Total 360, Bleach solution, Vital Oxide, and Peroxide Multi-Surface Cleaner) were evaluated against Murine Hepatitis Virus A59 (MHV) as a surrogate coronavirus for SARS-CoV-2. MHV in cell culture medium was inoculated onto four materials: stainless steel, latex-painted drywall tape, Styrene Butadiene rubber (rubber), and bus seat fabric. Immediately (T0) or 2-hr (T2) post-inoculation, disinfectants were applied by trigger-pull or electrostatic sprayer and either held for recommended contact times (Spray only) or immediately wiped (Spray and Wipe). Recovered infectious MHV was quantified by median tissue culture infectious dose assay. Bleach solution, Clorox Total 360, and Vital Oxide were all effective (>3-log 10 reduction or complete kill of infectious virus) with both the Spray Only and Spray and Wipe methods on stainless steel, rubber, and painted drywall tape when used at recommended contact times at both T0 and T2 hr. Multi-Surface Cleaner unexpectedly showed limited efficacy against MHV on stainless steel within the recommended contact time; however, it showed increased (2.3 times greater efficacy) when used in the Spray and Wipe method compared to Spray Only. The only products to achieve a 3-log 10 reduction on fabric were Vital Oxide and Clorox Total 360; however, the efficacy of Vital Oxide against MHV on fabric was reduced to below 3-log 10 when applied by an electrostatic sprayer compared to a trigger-pull sprayer. This study highlights the importance of considering the material, product, and application method when developing a disinfection strategy for coronaviruses on high-touch surfaces. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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