| Autor: |
Banchelli F; Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, 41100 Modena, Italy.; Unit of Statistical and Methodological Support to Clinical Research, University Hospital of Modena, 41100 Modena, Italy., Negro P; Immunohaematology and Transfusion Medicine Unit, Inter-Company Department of Transfusion Medicine (IDTM) of Local Health Unit (LHU) of Lecce, Vito Fazzi Hospital, 73100 Lecce, Italy., Guido M; Laboratory of Hygiene, Department of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy., D'Amico R; Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, 41100 Modena, Italy.; Unit of Statistical and Methodological Support to Clinical Research, University Hospital of Modena, 41100 Modena, Italy., Fittipaldo VA; IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, 20156 Milan, Italy., Grima P; Infectious Diseases Unit, Vito Fazzi Hospital, 73100 Lecce, Italy., Zizza A; Institute of Clinical Physiology, National Research Council, 73100 Lecce, Italy. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical medicine [J Clin Med] 2022 May 27; Vol. 11 (11). Date of Electronic Publication: 2022 May 27. |
| DOI: |
10.3390/jcm11113029 |
| Abstrakt: |
The SARS-CoV-2 infection has caused over 422 million contagions and 5.8 million deaths resulting in a global health crisis. Several studies have investigated the risk factors predisposing to the infection and reported that the host susceptibility can be linked to the ABO blood group, but the current evidence is controversial. We systematically searched for articles in EMBASE, PubMed, and Cochrane library published up to 7 May 2021 to explore the association of the ABO blood group with the susceptibility to SARS-CoV-2 infection. All studies in people undergoing SARS-CoV-2 test controls were included. Odds ratios were obtained in each study and then synthesised by using meta-analysis. Overall, 22 articles were selected and more than 1,200,000 individuals of whom 74,563 resulted positive to SARS-CoV-2 and 1,166,717 resulted negative, were included in the meta-analysis. Overall, 487,985 subjects had blood group A, 151,879 had group B, 52,621 had group AB, and 548,795 had group O. Group O was slightly less associated with infection, as compared to the other three blood groups (OR = 0.91, 95% CI = 0.85-0.99, p = 0.02). Conversely, group A was slightly more associated with infection, as compared to the other three groups (OR = 1.06, 95% CI = 1.00-1.13, p = 0.04). This meta-analysis shows associations between blood groups and SARS-CoV-2 infection and supports the hypothesis that blood type O may have a slightly lower risk of infection, whereas blood type A may have a slightly higher risk of infection. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
