Percutaneous Ablation of Metastatic Lymph Nodes: An Insight from the Comparison of Efficacy and Safety Between Cryoablation and Radiofrequency Ablation.

Autor: Filippiadis DK; 2nd Department of Radiology, Medical School, University General Hospital 'ATTIKON', National and Kapodistrian University of Athens,, 1 Rimini str, 12462, Haidari/Athens, Greece. dfilippiadis@yahoo.gr., Pua U; Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore., Georgiadi E; 2nd Department of Radiology, Medical School, University General Hospital 'ATTIKON', National and Kapodistrian University of Athens,, 1 Rimini str, 12462, Haidari/Athens, Greece., Quek LHH; Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore., Kelekis A; 2nd Department of Radiology, Medical School, University General Hospital 'ATTIKON', National and Kapodistrian University of Athens,, 1 Rimini str, 12462, Haidari/Athens, Greece., How GY; Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore., Kelekis N; 2nd Department of Radiology, Medical School, University General Hospital 'ATTIKON', National and Kapodistrian University of Athens,, 1 Rimini str, 12462, Haidari/Athens, Greece.
Jazyk: angličtina
Zdroj: Cardiovascular and interventional radiology [Cardiovasc Intervent Radiol] 2022 Aug; Vol. 45 (8), pp. 1134-1140. Date of Electronic Publication: 2022 Jun 09.
DOI: 10.1007/s00270-022-03191-2
Abstrakt: Purpose: To retrospectively compare efficacy and safety of computed tomography (CT)-guided percutaneous ablation of metastatic lymph nodes (LN) between cryoablation (CA) and radiofrequency ablation (RFA).
Materials and Methods: A bi-central institutional database research identified 28 patients (42 metastatic LNs) who underwent percutaneous CT-guided ablation. RFA group included 18 patients/26 tumors; CA group included 10 patients/16 tumors. Contrast-enhanced CT or MRI was used for post-ablation follow-up. Patient and tumor characteristics, technical and clinical success on a per tumor and a per patient basis and complication rates were recorded, evaluated and compared between the 2 groups.
Results: Both RFA and CA groups had the same median tumor size (2.00 vs. 2.20 cm, p = 0.257), the same median follow-up time (20.50 vs. 20.00 months, p = 0.923) and the same median length of hospital stay (1.00 vs. 1.00 days, p = 0.283). CA group had a higher median procedure time (110.50 vs. 52.00 min, p = 0.001). On a per lesion basis, the overall complete response post-ablation was 88.46% (23/26 lesions) in the RFA and 93.75% (15/16 lesions) in the CA group; no association was revealed between local tumor control and ablation technique (p = 0.709). No complications were recorded in both Groups. On a per patient basis, CA had a longer disease-free interval (24.00 vs. 14.50, p = 0.012) which, however, did not affect the overall survival between the two techniques (26.0 vs. 22.0, p = 0.099 for CA and RFA respectively).
Conclusion: Our limited data suggest that CT-guided RFA and CA are equally effective on terms of efficacy and safety for the treatment of metastatic lymph nodes.
(© 2022. Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).)
Databáze: MEDLINE
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