Epidemiology beyond its limits.

Autor: McCullough LE; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Maliniak ML; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Amin AB; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Baker JM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Baliashvili D; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Barberio J; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Barrera CM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Brown CA; Amgen Inc., Thousand Oaks, CA, USA., Collin LJ; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Freedman AA; Institute for Policy Research, Northwestern University, Evanston, IL, USA., Gibbs DC; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Haddad MB; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Hall EW; School of Public Health, Oregon Health & Science University, Portland, OR, USA., Hamid S; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Harrington KRV; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Holleman AM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Kaufman JA; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Khan MA; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Labgold K; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Lee VC; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Malik AA; Yale Institute for Global Health, Yale University, New Haven, CT, USA., Mann LM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Marks KJ; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Nelson KN; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Quader ZS; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Ross-Driscoll K; Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA., Sarkar S; ViiV Healthcare, Research Triangle Park, NC, USA., Shah MP; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Shao IY; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Smith JP; Department of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA., Stanhope KK; Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA., Valenzuela-Lara M; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Van Dyke ME; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Vyas KJ; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Lash TL; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Jazyk: angličtina
Zdroj: Science advances [Sci Adv] 2022 Jun 10; Vol. 8 (23), pp. eabn3328. Date of Electronic Publication: 2022 Jun 08.
DOI: 10.1126/sciadv.abn3328
Abstrakt: In 1995, journalist Gary Taubes published an article in Science titled "Epidemiology faces its limits," which questioned the utility of nonrandomized epidemiologic research and has since been cited more than 1000 times. He highlighted numerous examples of research topics he viewed as having questionable merit. Studies have since accumulated for these associations. We systematically evaluated current evidence of 53 example associations discussed in the article. Approximately one-quarter of those presented as doubtful are now widely viewed as causal based on current evaluations of the public health consensus. They include associations between alcohol consumption and breast cancer, residential radon exposure and lung cancer, and the use of tanning devices and melanoma. This history should inform current debates about the reproducibility of epidemiologic research results.
Databáze: MEDLINE