FDA Emergency Use Authorization-Approved Novel Coronavirus Disease 2019, Pressure-Regulated, Mechanical Ventilator Splitter That Enables Differential Compliance Multiplexing.

Autor:	Paulsen MJ; From the Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Zhu Y; From the Department of Cardiothoracic Surgery, Stanford University, Stanford, California.; Department of Bioengineering, Stanford University, Stanford, California., Park MH; From the Department of Cardiothoracic Surgery, Stanford University, Stanford, California.; Department of Mechanical Engineering, Stanford University, Stanford, California., Imbrie-Moore AM; From the Department of Cardiothoracic Surgery, Stanford University, Stanford, California.; Department of Mechanical Engineering, Stanford University, Stanford, California., Baker S; Department of Comparative Medicine, Stanford University, Stanford, California., Walter Edmonston D; Bloom Energy, San Jose, California., Dawson T; Bloom Energy, San Jose, California., Ly E; Bloom Energy, San Jose, California., Martin Bell S; Bloom Energy, San Jose, California., Tran NA; From the Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Jung J; From the Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Cedarleaf-Pavy J; Bloom Energy, San Jose, California., Sridhar KR; Bloom Energy, San Jose, California., Venkataraman V; Bloom Energy, San Jose, California., Woo YJ; From the Department of Cardiothoracic Surgery, Stanford University, Stanford, California.; Department of Bioengineering, Stanford University, Stanford, California.
Jazyk:	angličtina
Zdroj:	ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2022 Oct 01; Vol. 68 (10), pp. 1228-1230. Date of Electronic Publication: 2022 Jun 03.
DOI:	10.1097/MAT.0000000000001756
Abstrakt:	Infection with the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may cause viral pneumonia and acute respiratory distress syndrome (ARDS). Treatment of ARDS often requires mechanical ventilation and may take weeks for resolution. In areas with a large outbreaks, there may be shortages of ventilators available. While rudimentary methods for ventilator splitting have been described, given the range of independent ventilatory settings required for each patient, this solution is suboptimal. Here, we describe a device that can split a ventilator among up to four patients while allowing for individualized settings. The device has been validated in vitro and in vivo . Competing Interests: Disclosure: The authors have no conflicts of interest to report. (Copyright © ASAIO 2022.)
Databáze:	MEDLINE
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