Association between Duddingtonia flagrans, dimethylsulfoxide and ivermectin for the control of Rhabditis spp. in cattle.

Autor: Sobral SA; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Ferraz CM; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Souza RIL; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Queiroz LM; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Reinó N; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Junior OLF; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Tobias FL; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Correia JAL; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil., Araújo JV; Departamento de Veterinária, Universidade Federal de Viçosa - UFV, Viçosa, MG, Brazil., Vilela VRL; Departamento de Medicina Veterinária, Instituto Federal da Paraíba - IFPB, Sousa, PB, Brazil. vinicius.vilela@ifpb.edu.br., Soares FEF; Departamento de Química, Universidade Federal de Lavras - UFLA, Lavras, MG, Brazil., Braga FR; Departamento de Medicina Veterinária, Universidade Vila Velha - UVV, Vila Velha, ES, Brazil.
Jazyk: angličtina
Zdroj: Tropical animal health and production [Trop Anim Health Prod] 2022 Jun 06; Vol. 54 (4), pp. 198. Date of Electronic Publication: 2022 Jun 06.
DOI: 10.1007/s11250-022-03197-5
Abstrakt: Cattle parasitic otitis caused by the nematode Rhabditis spp. is a serious health problem in Brazil, a situation which is confounded by lack of effective control measures. In vitro studies associating biological and chemical control as an alternative method showed promising results. The objective was to evaluate the combined use of Duddingtonia flagrans (AC001), 10% dimethylsulfoxide (DMSO), and 1.9% ivermectin for the in vivo control of Rhabditis spp., in naturally infected Gyr cattle. For this purpose, 48 animals, whose infection in both ears was diagnosed, were randomly assigned to 6 groups: group 1 (ivermectin 1.9%); group 2 (10% DMSO); group 3 (AC001); group 4 (ivermectin 1.9% + 10% DMSO w/v); group 5 (1.9% ivermectin + AC001 w/v); group 6 (10% DMSO + AC001 v/v). The treatments were performed in a single dose, in the right ears, with the left ears remaining untreated, as a control group. There was a significant reduction (p < 0.01) in the number of nematodes in the treated groups in relation to the control, with the following best efficacies: groups 1 and 2, 47% and 52.9%, respectively, 7 days after treatment; groups 3, 4, and 5, 47.8%, 48.6% and 36.7%, respectively, 14 days post-treatment; group 6, 38.4%, 21 days post-treatment. It was concluded that the combination of chemical compounds and D. flagrans in a single application was effective for the in vivo control of Rhabditis spp. in naturally infected cattle.
(© 2022. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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