In-Hospital Outcomes of Coronary Artery Stenting in Patients With ST-Elevation Myocardial Infarction (STEMI) and Metabolic Syndrome: Insights From the National Inpatient Sample.

Autor:	Igbinosa O; Internal Medicine, Howard University Hospital, Washington, DC, USA., Brgdar A; Internal Medicine, Howard University Hospital, Washington, DC, USA., Asemota J; Internal Medicine, Howard University Hospital, Washington, DC, USA., Taha ME; Cardiovascular Medicine, Howard University, Washington, DC, USA., Yi J; Internal Medicine, Howard University Hospital, Washington, DC, USA., Lyonga Ngonge A; Internal Medicine, Howard University Hospital, Washington, DC, USA., Vanaparthy S; Internal Medicine, Howard University Hospital, Washington, DC, USA., Hammonds R; Internal Medicine, Howard University Hospital, Washington, DC, USA., Talbet J; Plastic and Reconstructive Surgery, Howard University Hospital, Washington, DC, USA., Omire-Mayor D; Internal Medicine, Howard University College of Medicine, Washington, DC, USA., Ngwa J; Internal Medicine, Howard University Hospital, Washington, DC, USA., Rizwan M; Internal Medicine, Howard University Hospital, Washington, DC, USA., Prafulla M; Cardiovascular Disease, Howard University Hospital, Washington, DC, USA., Opoku I; Cardiovascular Disease, Howard University Hospital, Washington, DC, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2022 May 02; Vol. 14 (5), pp. e24664. Date of Electronic Publication: 2022 May 02 (Print Publication: 2022).
DOI:	10.7759/cureus.24664
Abstrakt:	Background Metabolic syndrome (MetS) has been recognized as a global health problem. Concurrent MetS diagnosis in patients with ST-elevation myocardial infarction (STEMI) is becoming increasingly common. Given the paucity of studies on the impact of MetS on treatment outcomes in STEMI patients, the purpose of this study was to evaluate in-hospital mortality in STEMI patients with a concurrent MetS diagnosis undergoing a stenting procedure to treat their underlying coronary artery disease. Method Patients with or without MetS who underwent coronary stenting following STEMI between 2005 and 2014 were identified from the National Inpatient Sample database. Patients' demographics, comorbidities, and outcomes were compared using a t-test and Pearson's Chi-square test. In addition, 1:1 propensity score matching was performed for age, gender, and race. Results Out of 1,938,097 STEMI patients, 5,817 patients with MetS underwent coronary stenting following STEMI and were matched with 5,817 patients with no Mets. MetS group had significantly higher rates of diabetes, hypertension, hyperlipidemia, chronic kidney disease, and obstructive sleep apnea than the no MetS group but lower rates of heart failure and chronic obstructive pulmonary disease. In-hospital mortality following STEMI was significantly lower in patients with MetS (2.5% vs. 7.1%, p<0.001) and remained significant after adjusting for potential confounders (odds ratio (OR) 0.34, 95% confidence interval (95% CI) 0.28-0.42, p<0.0001). Conclusion Concurrent diagnosis of MetS among patients undergoing coronary stenting is associated with a decreased in-hospital mortality risk. The impact of specific MetS components on the observed reduction in mortality remains unclear and warrants evaluation in future studies. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Igbinosa et al.)
Databáze:	MEDLINE
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