Bell's palsy as a possible complication of mRNA-1273 (Moderna) vaccine against COVID-19.

Autor:	Poudel S; Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, United States., Nepali P; Bhimad Primary Health Care Center, Tanahun, Nepal.; Chitwan Medical College and Teaching Hospital, Chitwan, Nepal., Baniya S; Department of Emergency Medicine, Pokhara Academy of Health Sciences, Pokhara, Nepal., Shah S; Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, United States., Bogati S; B.P Koirala Institute of Health Sciences, Dharan, Nepal., Nepal G; Rani Primary Healthcare Centre, Biratnagar, Nepal., Ojha R; Department of Neurology, Tribhuvan University, Institute of Medicine, Kathmandu, Nepal., Edaki O; Department of Research and Academic Affairs, Larkin Community Hospital, South Miami, FL, United States., Lazovic G; Department of Emergency Medicine, Larkin Community Hospital Palm Springs Campus, Hialeah, FL, United States., Kara S; Department of Neurology, Larkin Community Hospital Palm Springs Campus, Hialeah, FL, United States.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2022 Jun; Vol. 78, pp. 103897. Date of Electronic Publication: 2022 May 31.
DOI:	10.1016/j.amsu.2022.103897
Abstrakt:	Introduction: Vero Cell, AstraZeneca, Janssen, mRNA-1273 (Moderna), and Pfizer COVID-19 vaccines have been authorized for emergency use in Nepal. These vacines have been linked to some adverse effects, including fever, myalgia, and headache. Furthermore Bell's Palsy a rare adverse effect was also reported to be associated with the use of mRNA-1273 (Moderna) vaccine in some patients. Case Presentation: In this case report we present a 17-year-old female who acquired Bell's Palsy following the administration of mRNA-1273 (Moderna) COVID-19 vaccination. Discussion: The possible etiology of BP that has been suggested is infection by reactivated viruses, such as the varicella-zoster virus (VZV), herpes simplex virus type 1 (HSV-1), human herpesvirus 6, and the Usutu virus, [1] the most accepted hypothesis is the one with reactivation of latent Herpes Simplex Virus type 1 in the geniculate ganglia of the facial nerves, an autoimmune mechanism through the mimicry of host molecules by the antigens of the vaccines. Conclusion: Though the extent of association between the mRNA vaccination and the development of Bell's Palsy has yet to be confirmed, this example highlights the need to closely monitor side effects and repercussions after receiving a new vaccine. (© 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.)
Databáze:	MEDLINE
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