Practice patterns amongst fetal centers performing intrauterine transfusions (PACT): An international survey study.

Autor: Donepudi R; Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Fetal Center, Houston, TX, USA. Electronic address: Roopali.Donepudi@bcm.edu., Antolin E; Fetal Medicine Unit, Department of Obstetrics and Gynecology, Hospital Universitario La Paz, Instituto de Investigación Sanitaria Hospital Universitario La Paz (IdiPAZ), Madrid, Spain., Molina F; Department of Obstetrics and Gynecology, Hospital Universitario Clinico San Cecilio, Granada, Spain; Instituto de Investigación Biosanitaria IBS, Granada, Spain., Sananes N; Department of Obstetrics and Gynecology, Strasbourg University Hospital, Strasbourg, France; INSERM UMR-S 1121 'Biomaterials and Bioengineering', Strasbourg University, Strasbourg, France., Khalil A; Fetal Medicine Unit, St George's Hospital, St George's University of London, London, UK; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St. George's University of London, Canada., Abbasi N; Fetal Medicine Unit, Department of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada., Sánchez-Durán MA; Maternal Fetal Medicine Unit, Department of Obstetrics. Vall d'Hebron University Hospital, Autonomous University of Barcelona, Barcelona, Spain., Hecher K; Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Fabietti I; Department of Obstetrics and Gynecology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Jouannic JM; Fetal Medicine department and French National Referral Center of Perinatal Hemobiology, Trousseau Hospital, APHP Sorbonne University, Paris, France., Ortiz JU; Division of Obstetrics and Perinatal Medicine, Department of Obstetrics and Gynecology, Technical University of Munich, Munich, Germany., Borrell A; Prenatal Diagnosis Unit, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Catalonia, Spain., Gielchinski Y; Fetal Therapy Helen-Schneider-Hospital for Women, Rabin Medical Center, Petah Tikva, Israel., Cortes MS; Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Fetal Center, Houston, TX, USA.
Jazyk: angličtina
Zdroj: European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 2022 Jul; Vol. 274, pp. 171-174. Date of Electronic Publication: 2022 May 30.
DOI: 10.1016/j.ejogrb.2022.05.027
Abstrakt: Objectives: Fetal anemia secondary to incompatibility between maternal-fetal blood types can result in hydrops and demise. Intrauterine transfusions have improved survival in experience centers. Our objective was to determine the practice patterns amongst fetal centers.
Study Design: Thirteen fetal centers across the world were surveyed. Results from all participating centers were recorded, analyzed, and presented as ratios. Questions on the survey were related to experience of the physician, preferred methods of transfusion, fetal surveillance, and timing of delivery.
Results: Differences amongst centers were as follows: 54% of the centers performed transfusions in operating room, the remaining did them in a clinic room or close to the operating room; 31% did not use maternal anesthesia, 31% used oral or intravenous sedation and 38% used a combination of local with oral or intravenous sedation. The similarities include: 84% performed intravenous transfusions, while 2 centers reported intraperitoneal and intracardiac transfusions were performed for very early cases; 85% of centers performed the last transfusion at 34-35 weeks and 77% electively delivered their patients at 37 weeks.
Conclusion: Method of transfusion and delivery timing was similar in most centers; however, differences were seen in location of procedure, anesthetic coverage, and surveillance. Further assessment is needed to determine if these differences in practice have any potential neonatal effects.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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