Expanding the precision oncology toolkit with micro-organospheres for early cancer diagnosis.

Autor: Vandana JJ; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY, NY 10065, USA; Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medicine, The Rockefeller University, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lacko LA; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY, NY 10065, USA., Chen S; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY, NY 10065, USA. Electronic address: shc2034@med.cornell.edu.
Jazyk: angličtina
Zdroj: Cell stem cell [Cell Stem Cell] 2022 Jun 02; Vol. 29 (6), pp. 873-875.
DOI: 10.1016/j.stem.2022.05.002
Abstrakt: Using an automatic microfluidics droplet platform, Ding et al. successfully replicated the tumor micro-environment by generating micro-organospheres, which were then used to predict the response to anti-tumor drugs. These miniature models could be obtained within an extremely short time frame of 14 days, amplifying their role in facilitating cancer treatment decisions.
Competing Interests: Declaration of interests S.C. is the co-founder of OncoBeat, LLC and a member of the Scientific Advisory Board of Cell Stem Cell.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE