Surgical and histological evidence of case reports showing Schwannomas in the nasal area.

Autor:	Galzignato PF; Department of Surgery, Dentistry, Paediatrics and Gynaecology-Unit of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy., Chirumbolo S; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address: salvatore.chirumbolo@univr.it., Cestaro W; ENT Consultant, Head and Neck Department, ULSS 2 Marca Trevigiana, Treviso, Italy., Scapinello A; Pathology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Bertossi D; Department of Surgery, Dentistry, Paediatrics and Gynaecology-Unit of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy., Nocini R; Department of Surgery, Dentistry, Gynaecology, and Paediatrics, Unit of Otorhinolaryngology, University of Verona, Verona, Italy.
Jazyk:	angličtina
Zdroj:	International journal of surgery case reports [Int J Surg Case Rep] 2022 May; Vol. 94, pp. 107165. Date of Electronic Publication: 2022 May 04.
DOI:	10.1016/j.ijscr.2022.107165
Abstrakt:	Introduction and Importance: Schwannomas are benign neurogenic neoplasms with an uncommon involvement of the nasal cavity and paranasal sinus, which usually appear as a painless formation. We report two cases of nasal schwannoma that was successfully treated by surgical excision with satisfactory functional outcomes. The aim of this study is to discuss the clinical assessment and imaging, (CT, MRI) differential diagnosis, histological examination, surgical approaches of this rarely encountered neoplasm in the sinus-nasal area. Case Presentation: Case 1: a 53 years-old Caucasian male, hospitalized in the ENT Department with a 5-month progressive history of right nasal obstruction without epistaxis was diagnosed as a Schwannoma following clinical, histology and ENT endoscopy examination. Case 2: a 45 years-old Caucasian male with asymptomatic swelling arising 4 months before in the nasal tip area with progressive nasal deformity, diagnosed as a schwannoma and analyzed with MRI. Clinical Discussion: Case 1: The patient had an uneventful post-operative course and a follow-up examination at 36 months showed no recurrence of the neoplasm with satisfactory functional result. Case 2: The patient had an uneventful post-operative course and a follow-up examination at 5 years showed no recurrence of the neoplasm and satisfactory aesthetic result. Conclusions: Schwannomas arising from sinonasal area are extremely rare, painless and with slow-growing evolution. The surgical option and histologic analysis are mandatory for a correct diagnosis. (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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