Prevalence of sarcopenia in women at stable weight phase after Roux-en-Y gastric bypass.

Autor:	Buzza AFB; Departamento de Clínica Médica, Serviço de Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (SEMPR), Curitiba, PR, Brasil, mestrado.deia@gmail.com., Machado CA; Centro de Ciências da Saúde da Faculdade de Medicina da Universidade Federal do Paraná, Curitiba, PR, Brasil., Pontes F; Centro de Ciências da Saúde da Faculdade de Medicina da Universidade Federal do Paraná, Curitiba, PR, Brasil., Sampaio LG; Centro de Ciências da Saúde da Faculdade de Medicina da Universidade Federal do Paraná, Curitiba, PR, Brasil., Contador JS; Hospital Evangélico Mackenzie, Curitiba, PR, Brasil., Sampaio CL; Centro de Ciências da Saúde da Faculdade de Medicina da Universidade Federal do Paraná, Curitiba, PR, Brasil., Radominski RB; Departamento de Clínica Médica, Serviço de Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (SEMPR), Curitiba, PR, Brasil., Boguszewski CL; Departamento de Clínica Médica, Serviço de Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (SEMPR), Curitiba, PR, Brasil., Borba VZC; Departamento de Clínica Médica, Serviço de Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (SEMPR), Curitiba, PR, Brasil.
Jazyk:	angličtina
Zdroj:	Archives of endocrinology and metabolism [Arch Endocrinol Metab] 2022 Jun 03; Vol. 66 (3), pp. 362-371. Date of Electronic Publication: 2022 Jun 02.
DOI:	10.20945/2359-3997000000494
Abstrakt:	Objective: Evaluating the prevalence of sarcopenia in women submitted to bariatric surgery - Roux-en-Y gastric bypass. Design: Observational, cross-sectional study. Subjects and Methods: Women (18-65 years old) who underwent bariatric surgery (BG) ≥ 2 years and reached stable weight ≥ 6 months, were investigated. Control group (CG) comprised non-operated matched women with obesity. Body composition was determined through dual-energy X-ray absorptiometry. Low lean mass (LLM) was defined as appendicular lean mass index (ALM kg/height m 2 ) < 5.5 kg/m 2 . Physical strength was assessed through dynamometer and sit-to-stand test (SST), whereas performance was assessed through 4-m gait speed and Short Physical Performance Battery Tests (SPPB). Sarcopenia was diagnosed in the presence of LLM and low strength. Results: One-hundred and twenty women (60 in each group, 50 ± 9.7 years old) were investigated. All anthropometric and body composition parameters were lower in BG than in CG, whereas strength and performance were similar between groups. Women with reduced strength presented high total fat mass and low physical activity level (p < 0.005). LLM was observed in 35% of BG and in 18.3% of CG (p = 0.04), whereas sarcopenia was diagnosed in 28.3% of BG and in 16.6% of CG (p = 0.12). Sarcopenic women in BG had better performance both in SST (p = 0.001) and SPPB (p = 0.004). Total lean mass (OR:1.41, 95% CI [1.18; 1.69], p < 0.001) and obesity (OR: 38.2 [2.27; 644.12], p < 0.001) were associated with sarcopenia in the multivariate analysis. Conclusion: Despite great weight loss, sarcopenia prevalence did not increase in BG and its presence was influenced by total lean mass and obesity.
Databáze:	MEDLINE
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