Phytochemistry and Biological Properties of Salvia verbenaca L.: A Comprehensive Review.

Autor: Mrabti HN; Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, BP 6203 Rabat, Morocco., El Menyiy N; Laboratory of Pharmacology, National Agency of Medicinal and Aromatic Plants, Taounate, 34025, Morocco., Charfi S; Biology and Health Laboratory, Department of Biology, Faculty of Science, Abdelmalek-Essaadi University, Tetouan, Morocco., Saber M; Laboratory of Nanotechnology, Materials and Environment, Department of Chemistry, Faculty of Science, Mohammed V University in Rabat, Morocco., Bakrim S; Molecular Engineering, Valorization and Environment Team, Polydisciplinary Faculty of Taroudant, Ibn Zohr University, Agadir, Morocco., Alyamani RA; Faculty of Applied Medical Sciences, Clinical Nutrition Department, Umm Al-Qura University, Makkah 24381, Saudi Arabia., Rauf A; Department of Chemistry, University of Swabi, Khyber Pakhtunkhwa (KP), Pakistan., Ali AMH; Department of Zoology and Entomology, Faculty of Science, Assiut University, Assiut, Egypt.; Department of Science Laboratories, College of Science and Arts, Qassim University, Ar Rass, Saudi Arabia., Abdallah EM; Department of Science Laboratories, College of Science and Arts, Qassim University, Ar Rass, Saudi Arabia., El Omari N; Laboratory of Histology, Embryology, and Cytogenetic, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco., Bouyahya A; Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco., Assaggaf H; Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 24381, Saudi Arabia.
Jazyk: angličtina
Zdroj: BioMed research international [Biomed Res Int] 2022 May 24; Vol. 2022, pp. 3787818. Date of Electronic Publication: 2022 May 24 (Print Publication: 2022).
DOI: 10.1155/2022/3787818
Abstrakt: The family Lamiaceae contains several plants used in traditional medicine to fight against different diseases . Salvia verbenaca L. ( S. verbenaca ) is one of the Lamiaceae species distributed around the Mediterranean regions. This plant exhibits different bioactive properties, including antibacterial, anticancer, antioxidant, antileishmanial, antidiabetic, immunomodulatory, and wound healing. This review was conducted to revise previous studies on S. verbenaca addressing its botanical description, geographical distribution, and phytochemical, pharmacological, and toxicological properties. Moreover, the main pharmacological actions of S. verbenaca major compounds were well investigated. Literature reports have revealed that S. verbenaca possesses a pivotal role in medicinal applications. The findings of this work noted that S. verbenaca was found to be rich in chemical compound classes such as terpenoids, phenolics, fatty acids, sterols, and flavonoids. Numerous studies have found that S. verbenaca essential oils and extracts have a wide range of biological effects. These results support the potential pharmacological properties of S. verbenaca and its traditional uses. This analysis can constitute a scientific basis for further refined studies on its pure secondary metabolites. Therefore, the outcome of the present work may support the perspective of identifying new therapeutical applications with detailed pharmacological mechanisms of S. verbenaca to prevent the development of some diseases such as neurodegenerative disorders. However, toxicological investigations into S. verbenaca are needed to assess any potential toxicity before it can be further used in clinical studies.
Competing Interests: No potential competing interest was reported by the authors.
(Copyright © 2022 Hanae Naceiri Mrabti et al.)
Databáze: MEDLINE
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