Use of traditional medicine and control of hypertension in 12 African countries.

Autor:	Lassale C; Cardiovascular Epidemiology and Genetics, Hospital del Mar Medical Research Institute IMIM, Barcelona, Spain classale@imim.es.; CIBER of Pathophysiology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain., Gaye B; Paris Cardiovascular Research Centre, INSERM U970, Université de Paris, Paris, France.; Cardiology department, University Hospital of Fann, Dakar, Senegal.; African Research Network, Dakar, Senegal.; Laboratoire de Physiologie et Explorations Fonctionnelles, Université Cheikh Anta Diop, Dakar, Senegal., Diop IB; Cardiology department, University Hospital of Fann, Dakar, Senegal., Mipinda JB; Cardiology department, Libreville University Hospital Center, Libreville, Komo-Mondah, Gabon., Kramoh KE; Institute of Cardiology of Abidjan, Abidjan, Côte d'Ivoire., Kouam Kouam C; Internal Medecine Department, Regional Hospital, Bafoussam, Cameroon., Ikama MS; Cardiology Department, National University Hospital of Brazzaville, Marien NGouabi University, Brazzaville, Congo., Takombe JL; Department of Internal Medicine of la Gombe, Ngaliema Hospital, Kinshasa, Congo (the Democratic Republic of the)., Damorou JM; Cardiology department, Central Hospital of Lome, Lome, Togo., Toure IA; Internal Medicine and Cardiology Department, University Hospital of Lamorde Niamey University, Niamey, Niger., Balde DM; Department of Cardiology, University Hospital of Conakry, Conakry, Guinea., Dzudie A; Cardiac Intensive Car & Cardiac Pacing Unit, Douala General Hospital, Douala, Cameroon., Houenassi M; National University Hospital Hubert K Maga, Cotonou, Benin., Kane A; Cardiology Department, University Hospital of Aristide Le Dantec, Dakar, Senegal., Kimbally-Kaki SG; Cardiology Department, National University Hospital of Brazzaville, Marien NGouabi University, Brazzaville, Congo., Kingue S; University of Yaoundé, Ministry of Public Health, Yaoundé, Cameroon., Limbole E; Department of Internal Medicine of la Gombe, Ngaliema Hospital, Kinshasa, Congo (the Democratic Republic of the).; Cardiology Department, University of Kinshasa Faculty of Medicine, Kinshasa, Congo (the Democratic Republic of the)., Mfeukeu Kuate L; Internal Medecine Department, Regional Hospital, Bafoussam, Cameroon.; Cardiology Department, Central Hospital of Yaounde, Yaounde, Cameroon., Ferreira B; Instituto do Coração, Maputo, Mozambique., Nhavoto C; Instituto do Coração, Maputo, Mozambique., Sidy Ali A; Department of cardiology, Cardiology clinics, Nouakchott, Mauritania., Azizi M; Hypertension unit, Georges Pompidou European Hospital, AP-HP Centre, Paris, France.; INSERM, Centre d'Investigation Clinique 1418, Paris, France.; Cardiovascular Epidemiology Department, Université de Paris, Paris, France., N'Guetta R; Institute of Cardiology of Abidjan, Abidjan, Côte d'Ivoire., Antignac M; Paris Cardiovascular Research Centre, INSERM U970, Université de Paris, Paris, France.; Department of Pharmacy, St Antoine Hospital, AP-HP Sorbonne Université, Paris, France., Jouven X; Paris Cardiovascular Research Centre, INSERM U970, Université de Paris, Paris, France.; Cardiovascular Epidemiology Department, Université de Paris, Paris, France.; Cardiology Department, Georges Pompidou European Hospital, AP-HP, Paris, France.; Paris-Sudden Death Expertise Center, Paris, France.
Jazyk:	angličtina
Zdroj:	BMJ global health [BMJ Glob Health] 2022 Jun; Vol. 7 (6).
DOI:	10.1136/bmjgh-2021-008138
Abstrakt:	Background: Use of traditional medicine (TM) is widespread in sub-Saharan Africa as a treatment option for a wide range of disease. We aimed to describe main characteristics of TM users and estimate the association of TM use with control of hypertension. Methods: We used data on 2128 hypertensive patients of a cross-sectional study (convenience sampling), who attended cardiology departments of 12 sub-Saharan African countries (Benin, Cameroon, Congo, Democratic Republic of the Congo, Gabon, Guinea, Côte d'Ivoire, Mauritania, Mozambique, Niger, Senegal, Togo). To model association of TM use with odds of uncontrolled, severe and complicated hypertension, we used multivariable mixed logistic regressions, and to model the association with blood pressure (systolic (SBP) and diastolic (DBP)) we used mixed linear models. All models were adjusted for age, sex, wealth, adherence to hypertension conventional treatment and country (random effect). Results: A total of 512 (24%) participants reported using TM, varying across countries from 10% in the Congo to 48% in Guinea. TM users were more likely to be men, living in rural area, poorly adhere to prescribed medication (frequently due to its cost). Use of TM was associated with a 3.87 (95% CI 1.52 to 6.22)/1.75 (0.34 to 3.16) mm Hg higher SBP/DBP compared with no use; and with greater odds of severe hypertension (OR=1.34; 95% CI 1.04 to 1.74) and of any hypertension complication (OR=1.27; 95% CI 1.01 to 1.60), mainly driven by renal complication (OR=1.57; 95% CI 1.07 to 2.29) after adjustment for measured confounders. Conclusions: The use of TM was associated with higher blood pressure, more severe hypertension and more complications in Sub-Saharan African countries. The widespread use of TM needs to be acknowledged and worked out to integrate TM safely within the conventional healthcare. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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