| Autor: |
Ryzhova MV; Burdenko Neurosurgical Center, Moscow, Russia., Galstyan SA; Burdenko Neurosurgical Center, Moscow, Russia., Telysheva EN; Burdenko Neurosurgical Center, Moscow, Russia. |
| Jazyk: |
ruština |
| Zdroj: |
Arkhiv patologii [Arkh Patol] 2022; Vol. 84 (3), pp. 65-75. |
| DOI: |
10.17116/patol20228403165 |
| Abstrakt: |
The review is focused on a relatively new research method in oncology - DNA methylation. Starting from the methylation of individual genes, the method is gradually expanding and becoming routine for studying the global structure of DNA methylation (methylome) in tumors of various localizations. For some tumors (carcinomas of the mammary and thyroid glands), the study of the global structure of DNA methylation is just beginning, while methylation classifiers have been proposed and successfully used in the Russian Federation for brain tumours and sarcomas. This article compares the fifth edition of the WHO Classification of tumours of the Central Neurvous System and the methylation brain classifier. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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