| Autor: |
Calderón GE; Instituto Nacional de Enfermedades Virales Humanas Dr. Julio I. Maiztegui, ANLIS, Pergamino, Buenos Aires, Argentina. E-mail: gcalderon@anlis.gob.ar., Provensal MC; Departamento de Ciencias Naturales, Universidad Nacional de Río Cuarto, Córdoba, Argentina.; Grupo de Investigaciones en Ecología Poblacional y Comportamental (GIEPCO, Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente (ICBIA) (UNRC-CONICET), Córdoba, Argentina.; Departamento de Ciencias Naturales, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Río Cuarto, Córdoba, Argentina., Martin ML; Instituto Nacional de Enfermedades Virales Humanas Dr. Julio I. Maiztegui, ANLIS, Pergamino, Buenos Aires, Argentina., Brito Hoyos DM; Departamento de Ciencias Naturales, Universidad Nacional de Río Cuarto, Córdoba, Argentina.; Grupo de Investigaciones en Ecología Poblacional y Comportamental (GIEPCO, Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente (ICBIA) (UNRC-CONICET), Córdoba, Argentina.; Departamento de Ciencias Naturales, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Río Cuarto, Córdoba, Argentina., García JB; Instituto Nacional de Enfermedades Virales Humanas Dr. Julio I. Maiztegui, ANLIS, Pergamino, Buenos Aires, Argentina., Gonzalez-Ittig RE; Instituto de Diversidad y Ecología Animal (IDEA), CONICET-UNC y Cátedra de Genética de Poblaciones y Evolución, Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Córdoba, Argentina., Levis S; Instituto Nacional de Enfermedades Virales Humanas Dr. Julio I. Maiztegui, ANLIS, Pergamino, Buenos Aires, Argentina. |
| Abstrakt: |
Since the identification of Junin virus in the 1950s, many studies were carried out in wild rodents within the endemic area of the Argentine Hemorrhagic Fever (AHF) that recorded also the activity of the lymphocytic choriomeningitis virus (LCMV) and the Latino virus (LATV). The absence of confirmed cases of AHF since the 1990s in the department of Rio Cuarto, Córdoba province, promoted ecoepidemiological surveillance of infection of Calomys musculinus (Junin virus reservoir) and the search of reservoirs of the other mammarenaviruses. During two years of seasonal sampling, with a capture, mark and release system, 857 rodents were captured, corresponding 57.3% to the rodent reservoirs: C. musculinus, C. venustus and Mus musculus, being the first the most abundant species. Antibodies were detected and the three viral agents were molecularly characterized, showing a prevalence of infection of 3.5% (9/254) for Junin virus, 100% (3/3) for LCMV and 24.1% (21/87) for LATV. In conclusion, we demonstrated Junin virus circulation in its rodent reservoir in a region considered historic for AHF with potential risk for the population and the spatio-temporal co-circulation of the three mammarenaviruses in the central region of Argentina. |
