| Autor: |
Sánchez-Prieto J, López-Pérez MJ |
| Jazyk: |
angličtina |
| Zdroj: |
Revista espanola de fisiologia [Rev Esp Fisiol] 1986 Dec; Vol. 42 (4), pp. 427-34. |
| Abstrakt: |
Highly purified brain mitochondria have been prepared by Na+, NH4+ or K+-containing two-phase systems. K+ stimulated the basal rate of respiration in the three mitochondrial preparations. However, K+ only stimulated the maximal oxidation rate (state 3 respiration rates) in those mitochondria prepared by K+-free (Na+ or NH4+-containing) two-phase systems. The increase in the basal rates of respiration induced by exogenous K+ correlates with the mitochondrial swelling rates. The stimulatory effect of K+ on maximal oxidation rates seems to reflect the K+ depletion of brain mitochondria when prepared by K+-free procedures. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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