Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection.

Autor: Rabaan AA; Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia.; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.; Department of Public Health and Nutrition, The University of Haripur, Haripur 22610, Pakistan., Mutair AA; Research Center, Almoosa Specialist Hospital, Al-Ahsa 36342, Saudi Arabia.; College of Nursing, Princess Norah Bint Abdulrahman University, Riyadh 11564, Saudi Arabia.; School of Nursing, Wollongong University, Wollongong, NSW 2522, Australia., Alhumaid S; Administration of Pharmaceutical Care, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa 31982, Saudi Arabia., Garout M; Department of Community Medicine and Health Care for Pilgrims, Faculty of Medicine, Umm Al-Qura University, Makkah 21955, Saudi Arabia., Alsubki RA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia., Alshahrani FS; Department of Internal Medicine, College of Medicine, King Saud University, Riyadh 11362, Saudi Arabia.; Department of Internal Medicine, Division of Infectious Diseases, College of Medicine, King Saud University Medical City, Riyadh 11451, Saudi Arabia., Alfouzan WA; Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait.; Microbiology Unit, Department of Laboratories, Farwania Hospital, Farwania 85000, Kuwait., Alestad JH; Immunology and Infectious Microbiology Department, University of Glasgow, Glasgow G1 1XQ, UK.; Microbiology Department, College of Medicine, Jabriya 46300, Kuwait., Alsaleh AE; Core Laboratory, Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia., Al-Mozaini MA; Immunocompromised Host Research Section, Department of Infection and Immunity, King Faisal Specialist Hospital and Research Centre, Riyadh 11564, Saudi Arabia., Koritala T; Division of Hospital Internal Medicine, Mayo Clinic Health System, Mankato, MN 56001, USA., Alotaibi S; Molecular Microbiology Department, King Fahad Medical City, Riyadh 11525, Saudi Arabia., Temsah MH; Pediatric Department, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia., Akbar A; Department of Microbiology, University of Balochistan, Quetta 87300, Pakistan., Ahmad R; Department of Microbiology, The University of Haripur, Haripur 22610, Pakistan., Khalid Z; Department of Microbiology, The University of Haripur, Haripur 22610, Pakistan., Muhammad J; Department of Microbiology, The University of Haripur, Haripur 22610, Pakistan., Ahmed N; Department of Medical Microbiology & Parasitology, School of Medical Sciences, University Sains Malaysia, Kota Bharu 16150, Kelantan, Malaysia.
Jazyk: angličtina
Zdroj: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2022 May 20; Vol. 58 (5). Date of Electronic Publication: 2022 May 20.
DOI: 10.3390/medicina58050680
Abstrakt: Measles is an RNA virus infectious disease mainly seen in children. Despite the availability of an effective vaccine against measles, it remains a health issue in children. Although it is a self-limiting disease, it becomes severe in undernourished and immune-compromised individuals. Measles infection is associated with secondary infections by opportunistic bacteria due to the immunosuppressive effects of the measles virus. Recent reports highlight that measles infection erases the already existing immune memory of various pathogens. This review covers the incidence, pathogenesis, measles variants, clinical presentations, secondary infections, elimination of measles virus on a global scale, and especially the immune responses related to measles infection.
Databáze: MEDLINE