| Autor: |
Al-Makhamreh H; Department of Cardiology, School of Medicine, University of Jordan, Amman 11972, Jordan., Alrabadi N; Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Haikal L; School of Medicine, University of Jordan, Amman 11972, Jordan., Krishan M; School of Medicine, University of Jordan, Amman 11972, Jordan., Al-Badaineh N; School of Medicine, University of Jordan, Amman 11972, Jordan., Odeh O; School of Medicine, University of Jordan, Amman 11972, Jordan., Barqawi T; School of Medicine, University of Jordan, Amman 11972, Jordan., Nawaiseh M; King Hussein Medical Center, Royal Medical Services, Amman 11855, Jordan., Shaban A; King Hussein Cancer Center, Amman 11941, Jordan., Abdin B; School of Medicine, University of Jordan, Amman 11972, Jordan., Khamies L; Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Hammoudeh A; Department of Cardiology, Istishari Hospital, Amman 11184, Jordan. |
| Abstrakt: |
(1) Background: Atrial fibrillation (AF) is the most common arrhythmia causing an increased risk of mortality and morbidity. It is classified into paroxysmal and non-paroxysmal AF depending on the duration and frequency of the episodes. (2) Aims: Our goal was to investigate and compare the clinical profiles, risk of co-morbidities, the use of oral anticoagulation, and outcomes of patients with paroxysmal and non-paroxysmal AF in inpatient and outpatient settings. (3) Methods: Data were extracted from 28 different hospitals and centers in Jordan with a total of 2160 patients enrolled in the study using an observational non-interventional study model. The clinical features and the use of oral anticoagulants were compared in patients with paroxysmal and non-paroxysmal AF. (4) Results: Paroxysmal AF was documented in 35.6% (769) of the patients and non-paroxysmal types in 63.9% (1380); in addition, the type of AF was unknown in 11 (0.5%) patients. Our results showed that non-paroxysmal AF patients tend to be older with more co-morbidities and higher CHA2DS2-VASC and HAS-BLED scores. They also have higher rates of hypertension and diabetes. Anticoagulant, antiarrhythmic, and diuretic agents, overall, were used more in non-paroxysmal AF than paroxysmal AF. Hospital admissions were also more frequent in non-paroxysmal AF due to various factors, some of which are heart failure, bleeding risk, and COPD. (5) Conclusions: Non-paroxysmal AF is more common among Jordanian AF patients. The prevalence of comorbidities and the use of different types of therapies, especially anticoagulants, were higher in these patients. |
