Influence of the SARS-CoV-2 pandemic on paediatric patients with type 1 diabetes mellitus after one year of follow-up.

Autor:	Gimeno-Hernández Garza V; Pediatrics, Hospital Universitario Miguel Servet, Zaragoza, Aragón, Spain., Antoñanzas Torres I; Pediatrics, Hospital Universitario Miguel Servet, Zaragoza, Aragón, Spain., Pitarch Roca E; Pediatrics, Hospital Universitario Miguel Servet, Zaragoza, Aragón, Spain., Vázquez Sánchez M; Pediatrics, Hospital Universitario Miguel Servet, Zaragoza, Aragón, Spain., Ferrer Lozano M; Pediatrics, Hospital Universitario Miguel Servet, Zaragoza, Aragón, Spain., de Arriba Muñoz A; Pediatrics, Hospital Universitario Miguel Servet, Zaragoza, Aragón, Spain.
Jazyk:	angličtina
Zdroj:	Journal of pediatric endocrinology & metabolism : JPEM [J Pediatr Endocrinol Metab] 2022 May 30; Vol. 35 (7), pp. 867-873. Date of Electronic Publication: 2022 May 30 (Print Publication: 2022).
DOI:	10.1515/jpem-2022-0222
Abstrakt:	Objectives: Lockdown during the SARS-CoV-2 pandemic generated uncertainty regarding its effects on the control of type 1 diabetes (DM1). Our study aims to evaluate the influence of the pandemic on the control of paediatric patients with DM1. Methods: Longitudinal, retrospective, observational study in patients with DM1 attended between 15/10/2019 and 15/03/2020. Data were collected at that visit and at the three subsequent visits. The second was remote in 50% of cases. The variables analysed were: type of insulin therapy, time in range (TIR), time in hypoglycaemia (THypo), time in hyperglycaemia (THyper), coefficient of variation (CV), glycosylated haemoglobin, insulin requirements and anthropometric data. Results: 157 patients were recruited. At the post-lockdown visit, the TIR increased and the THyper decreased with respect to the first (p<0.00) and second (p<0.00) visits. Patients treated with subcutaneous infusion showed a higher TIR at the third visit (p=0.03) and lower insulin requirements at the fourth visit (p=0.03) compared to patients treated with multiple doses. Patients with a remote visit presented a higher TIR (p<0.00), a lower THyper (p=0.00) and lower insulin requirements (p=0.01) at the next visit. Patients aged less than 6 years presented a lower glycosylated haemoglobin (p=0.01) and insulin requirements at the third (p=0.03) and fourth (p=0.01) visits, and a lower increase in body mass index (p=0.03) over the year. Conclusions: Metabolic control improved at the post-lockdown visit. Patients treated with subcutaneous infusion, those who had a remote visit during strict lockdown and those aged less than 6 years had a better evolution. (© 2022 Walter de Gruyter GmbH, Berlin/Boston.)
Databáze:	MEDLINE
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