Aggregatibacter actinomycetemcomitans: From Basic to Advanced Research.

Autor: Hbibi A; Research laboratory in oral biology and biotechnology, Faculty of dental medicine, Mohammed V University in Rabat, Rabat, Morocco. abdelhadi.hbibi@um5s.net.ma.; Centre des Soins Dentaires, Hôpital Provincial Moulay Abdellah, Salé, Morocco. abdelhadi.hbibi@um5s.net.ma., Bouziane A; Department of Periodontology, Faculty of Dental Medicine, Biostatistical Clinical and Epidemiological Research Laboratory, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco., Lyoussi B; Laboratory of Physiology, Pharmacology and Environmental Health, Faculty of Science, University Sidi Mohammed Ben Abdellah, Fez, Morocco., Zouhdi M; Department of Microbiology, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco., Benazza D; Department of Periodontology, Faculty of Dental Medicine, Mohammed V University in Rabat, Rabat, Morocco.
Jazyk: angličtina
Zdroj: Advances in experimental medicine and biology [Adv Exp Med Biol] 2022; Vol. 1373, pp. 45-67.
DOI: 10.1007/978-3-030-96881-6_3
Abstrakt: Aggregatibacter actinomycetemcomitans is a major periodontal pathogen that was identified firstly in actinomycotic lesions and later in advanced forms of periodontal diseases as well as in oral cavity of healthy subjects. The particular pathogenicity of this specie makes it a target for extensive studies both at fundamental and practical scales. The current advances in experimental and clinical research related to this bacterium focus the light on epidemiologic features, virulence, and invasiveness aspects as well as on identification challenges, bacterial susceptibility, and anti-virulence strategies. The present chapter provide to scientists and periodontal researchers a comprehensive overview on the main advances made in this field with a special focus on epidemiologic dissemination, microbial diagnosis, virulence factors and clinical implementations of such progress.
(© 2022. The Author(s), under exclusive license to Springer Nature Switzerland AG.)
Databáze: MEDLINE