Unique Isospora -associated histologic lesions in white-rumped shama ( Copsychus malabaricus ).

Autor: Wong TS; San Diego Zoo Wildlife Alliance, San Diego, CA.; University of California, Davis, Davis, CA., Stalis IH; San Diego Zoo Wildlife Alliance, San Diego, CA., Witte C; San Diego Zoo Wildlife Alliance, San Diego, CA., Kubiski SV; San Diego Zoo Wildlife Alliance, San Diego, CA.
Jazyk: angličtina
Zdroj: Veterinary pathology [Vet Pathol] 2022 Sep; Vol. 59 (5), pp. 869-872. Date of Electronic Publication: 2022 May 25.
DOI: 10.1177/03009858221098425
Abstrakt: Twenty-one white-rumped shamas (19 necropsied, 2 biopsied) ( Copsychus malabaricus ) housed at the San Diego Zoo between 1992 and 2020 were diagnosed with Isospora infection based on evaluation of histologic sections. Review of these cases revealed a consistent histologic lesion characterized by nodular aggregates of atypical epithelioid macrophages containing few intracytoplasmic protozoa, with or without lymphocytic infiltrates. Of the 19 necropsied cases, 16 (84%) had systemic lesions variably affecting the liver, spleen, gastrointestinal tract, lung, pancreas, connective tissues, or bone marrow, while all 21 diagnosed cases had skin involvement. The findings suggest that white-rumped shamas have a unique inflammatory response to isosporosis with a predilection for the skin. Skin may be a diagnostically sensitive sampling site for histologic diagnosis of Isospora in this species.
Databáze: MEDLINE