Computed Tomography Measured Psoas Cross Sectional Area Is Associated With Bone Mineral Density Measured by Dual Energy X-Ray Absorptiometry.

Autor:	Touban BM; Department of Orthopaedics, Brooke Army Medical Center, F. Edward Hebert School of Medicine - Uniformed Services University JBSA-Fort Sam Houston, TX USA., Sayegh MJ; Department of Orthopaedic Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell University, New Hyde Park, NY USA., Galina J; Department of Orthopaedics, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, NY USA. Electronic address: jessegal@buffalo.edu., Pavlesen S; Department of Orthopaedics, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, NY USA., Radwan T; Department of Orthopaedics, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, NY USA., Anders M; Department of Orthopaedics, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, NY USA.
Jazyk:	angličtina
Zdroj:	Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry [J Clin Densitom] 2022 Oct-Dec; Vol. 25 (4), pp. 592-598. Date of Electronic Publication: 2022 Apr 29.
DOI:	10.1016/j.jocd.2022.04.001
Abstrakt:	Dual-energy X-ray absorptiometry (DEXA) is the gold standard for osteoporosis screening and diagnosis. However, abdominal conventional computed tomography (CT) scan is widely available and multiple studies validated its use as a screening tool for osteoporosis compared to DEXA. The aim of this study was to determine the reliability of measuring core muscle size at the L3-L4 intervertebral disk space and estimate the relationship between core muscle size and bone mineral density (BMD) measured by DEXA. Retrospective chart review was performed on patients who underwent a DEXA scan for osteoporosis and a conventional abdominal CT scan within one-year apart. Total cross-sectional area (CSA) and Hounsfield Unit (HU) density of core muscles (psoas, paraspinal, and abdominal wall muscles) were measured. The association between psoas, paraspinal, abdominal, and central muscle CSA and Bone Mineral density (BMD) at L3, L4, total Lumbar Spine (LS), and right (R) and left (L) hip was estimated in crude and adjusted for age and sex linear regression models. Sixty patients (37 females, 23 males) met the inclusion criteria. The average interval between DEXA and abdominal CT scans was 3.6 months (range 0.1-10.2). Psoas muscle density was significantly positively associated with R hip BMD in both crude and adjusted models (β = 20.2, p = 0.03; β = 18.5, p = 0.01). We found a significant positive linear association between psoas muscle CSA and HU density with BMD of LS, R, and L hip in both crude and adjusted models. The strongest significant positive linear association was observed between total abdominal CSA and R hip BMD in crude and age and sex adjusted (ß = 85.3, p = 0.01; ß = 63.9, p = 0.02, respectively). CT scans obtained for various clinical indications can provide valuable information regarding BMD. This is the first study investigating association between BMD with central muscle density and CSA, and it demonstrated their significant positive the association. (Copyright © 2022 The International Society for Clinical Densitometry. All rights reserved.)
Databáze:	MEDLINE
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