Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine.

Autor: Algahtani HA; Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia; King Abdullah International Medical Research Center, Jeddah, Saudi Arabia; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. Electronic address: halgahtani@hotmail.com., Shirah BH; Department of Neuroscience, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia., Alwafi E; Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia; King Abdullah International Medical Research Center, Jeddah, Saudi Arabia; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Jazyk: angličtina
Zdroj: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2022 Jul; Vol. 218, pp. 107304. Date of Electronic Publication: 2022 May 19.
DOI: 10.1016/j.clineuro.2022.107304
Abstrakt: The coronavirus disease of 2019 (COVID-19) pandemic is caused by a novel coronavirus SARS-Cov-2. Four major vaccine types are being used to fight against this deadly pandemic and save precious human lives. All types of vaccines have been associated with a risk of neurological complications ranging from mild to severe. Cervical dystonia occurring after a COVID-19 vaccine was not previously reported in the literature. In this article, we describe a case of acute cervical dystonia occurring after the first dose of the BNT162b2 COVID-19 vaccine. We attribute the occurrence of cervical dystonia to the vaccine due to the temporal relationship. This report adds to the literature a possible rare side effect of a COVID-19 vaccine and contributes to the limited literature on potential neurological side effects of mRNA-based vaccines. The likely mechanism is autoimmune. Further research is needed to probe and study the exact mechanism.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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