Investigation of possible preventable causes of COVID-19 deaths in the Kampala Metropolitan Area, Uganda, 2020-2021.

Autor:	Eyu P; Public Health Fellowship Program, Kampala, Uganda. Electronic address: patricia.eyu@musph.ac.ug., Elyanu P; Baylor College of Medicine Children's Foundation, Uganda., Ario AR; Public Health Fellowship Program, Kampala, Uganda., Ntono V; Ministry of Health, Kampala, Uganda., Birungi D; Ministry of Health, Kampala, Uganda., Rukundo G; Ministry of Health, Kampala, Uganda., Nanziri C; Ministry of Health, Kampala, Uganda., Wadunde I; Public Health Fellowship Program, Kampala, Uganda., Migisha R; Public Health Fellowship Program, Kampala, Uganda., Katana E; Public Health Fellowship Program, Kampala, Uganda., Oumo P; Public Health Fellowship Program, Kampala, Uganda., Morukileng J; Public Health Fellowship Program, Kampala, Uganda., Harris JR; Centers for Disease Control and Prevention, Kampala, Uganda.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2022 Sep; Vol. 122, pp. 10-14. Date of Electronic Publication: 2022 May 17.
DOI:	10.1016/j.ijid.2022.05.033
Abstrakt:	Background: Identifying preventable causes of COVID-19 deaths is key to reducing mortality. We investigated possible preventable causes of COVID-19 deaths over a six-month period in Uganda. Methods: A case-patient was a person testing reverse transcription polymerase chain reaction-positive for SARS-CoV-2 who died in Kampala Metropolitan Area hospitals from August 2020 to February 2021. We reviewed records and interviewed health workers and case-patient caretakers. Results: We investigated 126 (65%) of 195 reported COVID-19 deaths during the investigation period; 89 (71%) were male, and the median age was 61 years. A total of 98 (78%) had underlying medical conditions. Most (118, 94%) had advanced disease at admission to the hospital where they died. A total of 44 (35%) did not receive a COVID-19 test at their first presentation to a health facility despite having consistent symptoms. A total of 95 (75%) needed intensive care unit admission, of whom 45 (47%) received it; 74 (59%) needed mechanical ventilation, of whom 47 (64%) received it. Conclusion: Among hospitalized patients with COVID-19 who died in this investigation, early opportunities for diagnosis were frequently missed, and there was inadequate intensive care unit capacity. Emphasis is needed on COVID-19 as a differential diagnosis, early testing, and care-seeking at specialized facilities before the illness reaches a critical stage. Increased capacity for intensive care is needed. Competing Interests: Conflict of interest The authors have no competing interests to declare. (Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu