Analgosedation in Critically Ill Adults Receiving Extracorporeal Membrane Oxygenation Support.

Autor:	Crow J; From the Department of Pharmacy, Johns Hopkins Hospital, Baltimore, Maryland., Lindsley J; From the Department of Pharmacy, Johns Hopkins Hospital, Baltimore, Maryland., Cho SM; Neurocritical Care Division, Departments of Neurology, Neurosurgery, and Anesthesiology & Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Wang J; Medical Critical Care Service, Department of Medicine, Inova Fairfax Medical Campus, Falls Church, Virginia., Lantry JH 3rd; Medical Critical Care Service, Department of Medicine, Inova Fairfax Medical Campus, Falls Church, Virginia., Kim BS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Tahsili-Fahadan P; Neurocritical Care Division, Departments of Neurology, Neurosurgery, and Anesthesiology & Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Medical Critical Care Service, Department of Medicine, Inova Fairfax Medical Campus, Falls Church, Virginia.; Department of Medical Education, University of Virginia, Inova Fairfax Medical Campus, Falls Church, Virginia.
Jazyk:	angličtina
Zdroj:	ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2022 Dec 01; Vol. 68 (12), pp. 1419-1427. Date of Electronic Publication: 2022 May 18.
DOI:	10.1097/MAT.0000000000001758
Abstrakt:	Extracorporeal membrane oxygenation (ECMO) is an increasingly utilized intervention for cardiopulmonary failure. Analgosedation during ECMO support is essential to ensure adequate pain and agitation control and ventilator synchrony, optimize ECMO support, facilitate patient assessment, and minimize adverse events. Although the principles of analgosedation are likely similar for all critically ill patients, ECMO circuitry alters medication pharmacodynamics and pharmacokinetics. The lack of clinical guidelines for analgosedation during ECMO, especially at times of medication shortage, can affect patient management. Here, we review pharmacological considerations, protocols, and special considerations for analgosedation in critically ill adults receiving ECMO support. Competing Interests: The authors have no conflicts of interests to report. (Copyright © ASAIO 2022.)
Databáze:	MEDLINE
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