Evaluation of IL-17A expressions in high-grade glial tumors receiving radiotherapy.

Autor:	Karaca F; Department of Radiation Oncology, Adana City Training and Research Hospital, Adana, Turkey., Keskin S; Department of Biostatistics, Van Yüzüncü Yıl University Medical Faculty, Van, Turkey., Mentes S; Department of Radiation Oncology, Adana City Training and Research Hospital, Adana, Turkey., Okten AI; Department of Neurosurgery, Adana City Training and Research Hospital, Adana, Turkey., Cavus G; Department of Neurosurgery, Adana City Training and Research Hospital, Adana, Turkey., Arslan A; Department of Neurosurgery, Adana City Training and Research Hospital, Adana, Turkey., Afsar CU; Department of Medical Oncology, Istinye University Medical Faculty, Liv Vadi Hospital, Istanbul, Turkey., Koksal F; Department of Microbiology, Çukurova University School of Medicine, Adana, Turkey.
Jazyk:	angličtina
Zdroj:	Nigerian journal of clinical practice [Niger J Clin Pract] 2022 May; Vol. 25 (5), pp. 582-588.
DOI:	10.4103/njcp.njcp_1408_21
Abstrakt:	Aim: In this study, we aimed to investigate the interleukin-17A (IL-17A) levels in patients with high-grade glial tumors before receiving radiotherapy, immediately after radiotherapy, and 3 months after radiotherapy. Patients and Methods: A total of 33 patients who applied to Adana City Training and Research Hospital, Department of Radiation Oncology between December 2016 and May 2018 was included in this study. A total of three blood samples was taken from each patient to assess IL-17A levels before and after radiotherapy and 3 months after the completion of radiotherapy. Results: The differences in IL-17A levels between genders were not statistically significant. IL-17A levels progressively decreased after the radiotherapy and 3 months after the radiotherapy as compared to the levels before radiotherapy. However, this was not statistically significant. IL-17A levels in the non-surviving patients were high before and after radiotherapy as compared to the surviving ones, but this was also not statistically significant. Conclusion: As compared to the period before radiotherapy, IL-17A levels tend to decrease in the period of acute and chronic phases of radiotherapy in all patient groups. Competing Interests: None
Databáze:	MEDLINE
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