| Autor: |
Colella M; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro' Via E. Orabona 4, 70125 Bari, Italy. renzo.luisi@uniba.it., Musci P; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro' Via E. Orabona 4, 70125 Bari, Italy. renzo.luisi@uniba.it., Andresini M; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro' Via E. Orabona 4, 70125 Bari, Italy. renzo.luisi@uniba.it., Spennacchio M; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro' Via E. Orabona 4, 70125 Bari, Italy. renzo.luisi@uniba.it., Degennaro L; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro' Via E. Orabona 4, 70125 Bari, Italy. renzo.luisi@uniba.it., Luisi R; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro' Via E. Orabona 4, 70125 Bari, Italy. renzo.luisi@uniba.it. |
| Abstrakt: |
In recent years, fluoroiodomethane (CH 2 FI) has emerged as an easy-to-handle, non-ozone depleting agent and readily available platform for monofluoromethylation strategies. Recent applications in nucleophilic substitutions, lithiation reactions, transition-metal catalyzed transformations, radical processes, and 18 F-radiolabelling chemistry showcase the potential of this reagent for the preparation of organofluorine compounds. In this minireview, we provide an update to the field covering the recent relevant literature on the use of CH 2 FI. |
