Secondary metabolites from an endophytic fungus Trichoderma erinaceum with antimicrobial activity towards Pythium ultimum .

Autor: Siebatcheu EC; Laboratory of Biochemistry, Faculty of Science, University of Douala, Douala, Cameroon., Wetadieu D; Department of Chemistry, University of Dschang, Dschang, Cameroon., Youassi Youassi O; Laboratory of Biochemistry, Faculty of Science, University of Douala, Douala, Cameroon., Bedine Boat MA; Department of Biochemistry, University of Yaoundé I, Yaoundé, Cameroon., Bedane KG; Department of Chemistry, Addis Ababa University, Addis Ababa, Ethiopia., Tchameni NS; Laboratory of Biochemistry, Faculty of Science, University of Douala, Douala, Cameroon., Sameza ML; Laboratory of Biochemistry, Faculty of Science, University of Douala, Douala, Cameroon.
Jazyk: angličtina
Zdroj: Natural product research [Nat Prod Res] 2023 Feb; Vol. 37 (4), pp. 657-662. Date of Electronic Publication: 2022 May 18.
DOI: 10.1080/14786419.2022.2075360
Abstrakt: Chemical investigation of the endophytic fungus, Trichoderma erinaceum , isolated from healthy and asymptomatic common bean field crop, resulted in the isolation of a new alkene, ( Z )-5-amino-5-(1,1,2-trihydroxybuta-1,3-dienyloxy)pentane-6,7,8,9-tetraol ( 1 ), together with five known compounds ( 2 - 6 ). The structures of the compounds were elucidated by analysis of their spectroscopic data including 1 D, 2 D NMR, ESI-HRMS and literature data. The organic crude extract and the compound isolated from T. erinaceum significantly (p ≤ 0.05) inhibited the mycelial growth of Pythium ultimum .
Databáze: MEDLINE