Changes in smell and taste perception related to COVID-19 infection: a case-control study.

Autor: Cattaneo C; Sensory & Consumer Science Lab (SCS_Lab), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133, Milan, Italy., Pagliarini E; Sensory & Consumer Science Lab (SCS_Lab), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133, Milan, Italy. ella.pagliarini@unimi.it., Mambrini SP; International Center for the Assessment of Nutritional Status (ICANS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133, Milan, Italy.; Laboratory of Metabolic Research, San Giuseppe Hospital, IRCCS Istituto Auxologico Italiano, 28824, Piancavallo, Italy., Tortorici E; Department of Cardiovascular Neural and Metabolic Sciences, San Luca Hospital, IRCCS Istituto Auxologico Italiano, 20149, Milan, Italy., Mené R; Department of Medicine and Surgery, University of Milano-Bicocca, 20126, Milan, Italy., Torlasco C; Department of Cardiovascular Neural and Metabolic Sciences, San Luca Hospital, IRCCS Istituto Auxologico Italiano, 20149, Milan, Italy., Perger E; Department of Medicine and Surgery, University of Milano-Bicocca, 20126, Milan, Italy.; Sleep Disorders Center and Department of Cardiology, San Luca Hospital, IRCCS Istituto Auxologico Italiano, 20149, Milan, Italy., Parati G; Department of Medicine and Surgery, University of Milano-Bicocca, 20126, Milan, Italy.; Sleep Disorders Center and Department of Cardiology, San Luca Hospital, IRCCS Istituto Auxologico Italiano, 20149, Milan, Italy., Bertoli S; International Center for the Assessment of Nutritional Status (ICANS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133, Milan, Italy.; Obesity Unit - Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, 20145, Milan, Italy.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2022 May 17; Vol. 12 (1), pp. 8192. Date of Electronic Publication: 2022 May 17.
DOI: 10.1038/s41598-022-11864-8
Abstrakt: The main aim of the present study was to psychophysically evaluate smell and taste functions in hospitalized COVID-19 patients and to compare those results with a group of healthy subjects. Another aim of the study was to assess the relationship of changes in patients' smell and taste functions with a number of clinical parameters, symptoms, and other physiological signs as well as with severity of disease. Olfactory and gustatory functions were tested in 61 hospitalized patients positive for SARS-CoV-2 infection and in a control group of 54 healthy individuals. Overall, we found a significant impairment of olfactory and gustatory functions in COVID-19 patients compared with the control group. Indeed, about 45% of patients self-reported complaints about or loss of either olfactory or gustatory functions. These results were confirmed by psychophysical testing, which showed a significantly reduced performance in terms of intensity perception and identification ability for both taste and smell functions in COVID-19 patients. Furthermore, gustatory and olfactory impairments tended to be more evident in male patients suffering from more severe respiratory failure (i.e., pneumonia with need of respiratory support need during hospitalization).
(© 2022. The Author(s).)
Databáze: MEDLINE
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