| Autor: |
Peng ZT; Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, China., Xia YJ; Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, China., Yashiro T; Cosmetic Division, Nabocul Cosmetics Company Limited, Tokyo, Japan., Gao X; Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, China., Dong TT; Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, China.; Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, China., Tsim KW; Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, China.; Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, China., Wang HY; Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, China.; Institute of Pharmacy, School of Pharmacy, Henan University, Kaifeng, China. |
| Abstrakt: |
Two new phenylpropanoids ( 1 and 2 ) and one new isoflavone glycoside ( 3 ), along with nine known compounds ( 4 - 12 ), were isolated from the pod of Ceratonia siliqua L. Their chemical structures were elucidated based on extensive spectroscopic analyses (1 D and 2 D NMR, UV, IR, and HRESIMS) and compared with the literature data. In addition, all isolated compounds were evaluated in vitro for inhibitory activity against acetylcholinesterase (AChE). Compounds 4 , 5 , and 12 showed inhibitory activity against acetylcholinesterase (AChE) with IC 50 values ranging from 15.0 to 50.2 μM. |
