Oxygenated right ventricular assist device with a percutaneous dual-lumen cannula as a bridge to lung transplantation.

Autor: Harano T; Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Division of Thoracic Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Chan EG; Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Furukawa M; Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Reck Dos Santos P; Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Morrell MR; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Sappington PL; Department of Medicine, West Virginia University, Morgantown, WV, USA., Sanchez PG; Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Jazyk: angličtina
Zdroj: Journal of thoracic disease [J Thorac Dis] 2022 Apr; Vol. 14 (4), pp. 832-840.
DOI: 10.21037/jtd-21-1199
Abstrakt: Background: Oxygenated right ventricular assist device (oxyRVAD) placement has become more streamlined with the introduction of the dual-lumen pulmonary artery cannula. Peripherally cannulated oxyRVAD may provide oxygenation support with right heart support as an alternative to venoarterial extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation.
Methods: A single-institution, retrospective analysis was performed on patients placed on oxyRVAD with a dual-lumen pulmonary artery cannula with the intention of bridging to lung transplantation in 2019.
Results: Four patients with idiopathic pulmonary fibrosis were placed on oxyRVAD as a bridge to transplantation. Two patients were extubated and ambulated while waiting for a lung offer, and two patients required conversion to venoarteriovenous ECMO (VAV ECMO) from oxyRVAD. The median waiting time for extracorporeal life support (ECLS) was 42 h. All patients underwent double lung transplantation. Two patients stayed on oxyRVAD, and one patient was placed on venovenous ECMO (VV ECMO) after transplantation. Primary graft dysfunction score at 72 h after transplantation was grade 1 in three patients and grade 3 in one patient.
Conclusions: Peripherally cannulated oxyRVAD with percutaneous dual-lumen venous cannula could be an ambulatory bridge for lung transplantation. It is unknown whether oxyRVAD is feasible as a long-term bridge to lung transplantation.
Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jtd.amegroups.com/article/view/10.21037/jtd-21-1199/coif). The authors have no conflicts of interest to declare.
(2022 Journal of Thoracic Disease. All rights reserved.)
Databáze: MEDLINE