Epidemiology, aetiology and treatment of skin and soft tissue infections: final report of a prospective multicentre national registry.

Autor: Esposito S; Department of Infectious Diseases, University of Salerno, Salerno, Italy., Pagliano P; Department of Infectious Diseases, University of Salerno, Salerno, Italy., De Simone G; Department of Infectious Diseases, University of Salerno, Salerno, Italy., Pan A; Department of Infectious Diseases, Istituti Ospitalieri of Cremona, Cremona, Italy., Brambilla P; Department of Infectious Diseases, Istituti Ospitalieri of Cremona, Cremona, Italy., Gattuso G; Department of Infectious Diseases, Carlo Poma Hospital, Mantova, Italy., Mastroianni C; Department of Public Health and Infectious Diseases, Sapienza University, Latina, Italy., Kertusha B; Department of Public Health and Infectious Diseases, Sapienza University, Latina, Italy., Contini C; Department of Medical Sciences, Section of Infectious Diseases and Dermatology, University of Ferrara, Ferrara, Italy., Massoli L; Department of Medical Sciences, Section of Infectious Diseases and Dermatology, University of Ferrara, Ferrara, Italy., Francisci D; Infectious Diseases Clinic, University Hospital 'S. Maria', University of Perugia, Perugia, Italy., Priante G; Infectious Diseases Clinic, University Hospital 'S. Maria', University of Perugia, Perugia, Italy., Libanore M; Infectious Diseases Unit, Department of Infectious Diseases, S. Anna University Hospital, Ferrara, Italy., Bicocchi R; Infectious Diseases Unit, Department of Infectious Diseases, S. Anna University Hospital, Ferrara, Italy., Borgia G; Department of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, Italy., Maraolo AE; Department of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, Italy., Brugnaro P; Infectious Diseases Department, Ospedale Civile 'SS. Giovanni e Paolo', Venice, Italy., Panese S; Infectious Diseases Department, Ospedale Civile 'SS. Giovanni e Paolo', Venice, Italy., Calabresi A; Emergency Department, Hospital 'Santi Antonio e Biagio e C. Arrigo', Alessandria, Italy., Amendola G; Emergency Department, Hospital 'Santi Antonio e Biagio e C. Arrigo', Alessandria, Italy., Savalli F; Infectious Diseases Unit, Hospital of Trapani, Trapani, Italy., Geraci C; Infectious Diseases Unit, Hospital of Trapani, Trapani, Italy., Tedesco A; Infectious Diseases Unit, Hospital Fracastoro San Bonifacio, Verona, Italy., Fossati S; Infectious Diseases Unit, University Hospital of Trieste, Trieste, Italy., Carretta A; Department of Infectious Diseases, University Hospital 'Ospedali Riuniti' of Foggia, Foggia, Italy., Santantonio T; Department of Infectious Diseases, University Hospital 'Ospedali Riuniti' of Foggia, Foggia, Italy., Cenderello G; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy., Crisalli MP; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy., Schiaroli E; Department of Medicine, Section of Infectious Diseases, University of Perugia, Perugia, Italy., Rovere P; Infectious Diseases Unit, Legnago Hospital, Verona, Italy., Masini G; Infectious Diseases Unit, Legnago Hospital, Verona, Italy., Ferretto R; Infectious Diseases Unit, 'Alto Vicentino' Santorso Hospital, Vicenza, Italy., Cascio A; Infectious Diseases Unit, Universita degli Studi di Palermo, Palermo, Italy., Colomba C; Infectious Diseases Unit, Universita degli Studi di Palermo, Palermo, Italy., Gioè C; Infectious Diseases Unit, Universita degli Studi di Palermo, Palermo, Italy., Tumbarello M; Institute of Infectious Diseases, Foundation Policlinico Universitario A. Gemelli IRCCS, Cattolica del Sacro Cuore University, Rome, Italy., Losito AR; Institute of Infectious Diseases, Foundation Policlinico Universitario A. Gemelli IRCCS, Cattolica del Sacro Cuore University, Rome, Italy., Foti G; Infetious Diseases Unit, 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy., Prestileo T; Infectious Diseases Unit, Arnas Civico Hospital, Palermo, Italy., Buscemi C; Infectious Diseases Unit, Arnas Civico Hospital, Palermo, Italy., Iaria C; Infectious Diseases Unit, Arnas Civico Hospital, Palermo, Italy., Iacobello C; Infectious Diseases Unit, Cannizzaro Hospital, Catania, Italy., Sonia S; Infectious Diseases Unit, Cannizzaro Hospital, Catania, Italy., Starnini G; Infectious Diseases Unit, Belcolle Hospital, Viterbo, Italy., Ialungo A; Infectious Diseases Unit, Belcolle Hospital, Viterbo, Italy., Sapienza M; UOC Medicina Interna, Ospedale Umberto I, Enna, Italy.
Jazyk: angličtina
Zdroj: Journal of chemotherapy (Florence, Italy) [J Chemother] 2022 Dec; Vol. 34 (8), pp. 524-533. Date of Electronic Publication: 2022 May 14.
DOI: 10.1080/1120009X.2022.2075170
Abstrakt: Skin and soft tissue infections (SSTIs) represent a heterogenous group of pathological conditions involving the skin or the underlying subcutaneous tissues, fascia and muscle, characterised by a considerable variety of clinical presentations, severity and possible aetiological pathogens. Although previous analyses on restricted types of SSTIs and population have already been published, we conducted a large nationwide surveillance program on behalf of the Italian Society of Infectious and Tropical Diseases to assess the clinical and microbiological characteristics of the whole SSTI spectrum, from mild to severe life-threatening infections, in both inpatients and outpatients and their management. Twenty-nine Infectious Diseases (ID) Centres throughout Italy collected prospectively data concerning both the clinical and microbiological diagnosis of patients affected by SSTIs via an electronic case report form. We included in our database all cases managed by ID specialists participating to the study, independently from their severity or the setting of consultation. Here, we integrated previous preliminary results analysing and reporting data referring to a 3-year period (October 2016-October 2019). During this period, the study population included 478 adult patients with diagnosis of SSTI. The type of infection diagnosed, the aetiological agent involved and some notes on antimicrobial susceptibilities were collected and reported herein. We also analysed the most common co-morbidities, the type and duration of therapy executed, before and after ID intervention and the length of stay. The results of our study provide information to better understand the national epidemiologic data and the current clinical management of SSTIs in Italy.
Databáze: MEDLINE
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