Relevant increase of CTX-M-producing Escherichia coli carriage in school-aged children from rural areas of the Bolivian Chaco in a three-year period.
| Autor: | Boncompagni SR; Department of Medical Biotechnologies, University of Siena, Santa Maria alle Scotte University Hospital, Siena, Italy., Micieli M; Department of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, Florence, Italy., Di Maggio T; Department of Medical Biotechnologies, University of Siena, Santa Maria alle Scotte University Hospital, Siena, Italy., Mantella A; Department of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, Florence, Italy., Villagrán AL; Hospital Básico Villa Montes, Villa Montes, Plurinational State of Bolivia., Briggesth Miranda T; Hospital Municipal de Camiri, Camiri, Plurinational State of Bolivia., Revollo C; Instituto Nacional de Laboratorios de Salud (INLASA), La Paz, Plurinational State of Bolivia., Poma V; Escuela de Salud del Chaco Tekove Katu, Gutierrez, Plurinational State of Bolivia., Gamboa H; Facultad Integral del Chaco, Universidad Autónoma Gabriel René Moreno, Camiri, Plurinational State of Bolivia., Spinicci M; Department of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, Florence, Italy; Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Strohmeyer M; Department of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, Florence, Italy., Bartoloni A; Department of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, Florence, Italy; Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Rossolini GM; Department of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, Florence, Italy; Clinical Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy., Pallecchi L; Department of Medical Biotechnologies, University of Siena, Santa Maria alle Scotte University Hospital, Siena, Italy. Electronic address: lucia.pallecchi@unisi.it. |
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| Jazyk: | angličtina |
| Zdroj: | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2022 Aug; Vol. 121, pp. 126-129. Date of Electronic Publication: 2022 May 12. |
| DOI: | 10.1016/j.ijid.2022.05.025 |
| Abstrakt: | Objectives: The aim of this study was to perform two cross-sectional surveys on the fecal carriage of CTX-M-producing Enterobacterales in school-aged children from rural areas of the Bolivian Chaco (2016 vs 2019). Methods: A total of 757 fecal samples were collected from school-aged children living in nine indigenous communities (n=337, 2016; n=420, 2019). After a first passage onto MacConkey agar (MCA), samples were plated onto MCA plus cefotaxime 2 µg/mL (MCA-CTX), and a loopful of the bacterial growth was used as a template for the detection of group 1, 2, 8/25, and 9 bla Results: Growth onto MCA-CTX was obtained with 208 samples (27.5%; 62/337, 2016; 146/420, 2019), of which 201 (96.6%) were positive for bla Conclusions: The present study demonstrated an alarming spread of CTX-M enzymes in rural areas of the Bolivian Chaco, where antibiotics consumption is limited. Further studies are encouraged to better understand the dissemination dynamics of such relevant resistance determinants. Competing Interests: Declaration of Competing Interest The authors have no competing interests to declare. (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| Databáze: | MEDLINE |
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