Variant calling from scRNA-seq data allows the assessment of cellular identity in patient-derived cell lines.

Autor: Ramazzotti D; Dept. of Medicine and Surgery, Univ. of Milan-Bicocca, Monza, Italy., Angaroni F; Dept. of Informatics, Systems and Communication, Univ. of Milan-Bicocca, Milan, Italy., Maspero D; Dept. of Informatics, Systems and Communication, Univ. of Milan-Bicocca, Milan, Italy.; Inst. of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Segrate, Milan, Italy., Ascolani G; Dept. of Informatics, Systems and Communication, Univ. of Milan-Bicocca, Milan, Italy., Castiglioni I; Dept. of Physics 'Giuseppe Occhialini', Univ. of Milan-Bicocca, Milan, Italy., Piazza R; Dept. of Medicine and Surgery, Univ. of Milan-Bicocca, Monza, Italy.; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre - B4, Milan, Italy., Antoniotti M; Dept. of Informatics, Systems and Communication, Univ. of Milan-Bicocca, Milan, Italy.; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre - B4, Milan, Italy., Graudenzi A; Dept. of Informatics, Systems and Communication, Univ. of Milan-Bicocca, Milan, Italy. alex.graudenzi@unimib.it.; Inst. of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Segrate, Milan, Italy. alex.graudenzi@unimib.it.; Bicocca Bioinformatics, Biostatistics and Bioimaging Centre - B4, Milan, Italy. alex.graudenzi@unimib.it.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2022 May 12; Vol. 13 (1), pp. 2718. Date of Electronic Publication: 2022 May 12.
DOI: 10.1038/s41467-022-30230-w
Databáze: MEDLINE