Spectral homogeneity of human platelets investigated by SERS.

Autor: Zyubin A; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Rafalskiy V; REC «Clinical Trials Center», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Lopatin M; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Demishkevich E; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia.; Institute of Physics, Saratov State University, Saratov, Russia., Moiseeva E; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Matveeva K; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Kon I; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Khankaev A; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Kundalevich A; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia.; Institute of Physics, Saratov State University, Saratov, Russia., Butova V; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Lipnevich L; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Lyatun I; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Samusev I; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia., Bryukhanov V; REC «Fundamental and Applied Photonics, Nanophotonics», Immanuel Kant Baltic Federal University, Kaliningrad, Kaliningrad Region, Russia.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2022 May 11; Vol. 17 (5), pp. e0265247. Date of Electronic Publication: 2022 May 11 (Print Publication: 2022).
DOI: 10.1371/journal.pone.0265247
Abstrakt: This paper describes a detailed study of the spectral homogeneity of human platelets using Surface-enhanced Raman spectroscopy (SERS). We used a combined approach based on multivariate methods as principal component analysis and pair correlation algorithms to investigate platelets spectral properties. The correlation coefficients for each sample have been calculated, and the average coefficient of determination has been estimated. The high degree of spectral homogeneity inside one probe and between them has been revealed. The prospects of obtained results usage for pathologies based on platelet conformations during cardiovascular diseases have been demonstrated.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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