Adsorption of tetrakis(4-sulfophenyl)porphyrin onto liposomal surfaces composed of neutral diacylphosphatidylcholine and release by cyclodextrin.
| Autor: | Tsuchiya Y; Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University 1-4-1 Kagamiyama Higashi-Hiroshima 739-8527 Japan., Nakaya T; Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University 1-4-1 Kagamiyama Higashi-Hiroshima 739-8527 Japan., Kakigi T; Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University 1-4-1 Kagamiyama Higashi-Hiroshima 739-8527 Japan., Sugikawa K; Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University 1-4-1 Kagamiyama Higashi-Hiroshima 739-8527 Japan., Ikeda A; Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University 1-4-1 Kagamiyama Higashi-Hiroshima 739-8527 Japan. |
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| Jazyk: | angličtina |
| Zdroj: | RSC advances [RSC Adv] 2018 Mar 27; Vol. 8 (22), pp. 11930-11934. Date of Electronic Publication: 2018 Mar 27 (Print Publication: 2018). |
| DOI: | 10.1039/c8ra01411f |
| Abstrakt: | Anionic tetrakis(4-sulfophenyl)porphyrin (TPPS) interacts with liposomal surfaces composed of neutral diacylphosphatidylcholine at high lipid concentrations. TPPS interacted with liposomal surfaces through four contact points. The association constant was obtained to be 9.0 × 10 5 M -4 . TPPS was peeled off the liposomal surfaces by the addition of cyclodextrin. Competing Interests: There are no conflicts to declare. (This journal is © The Royal Society of Chemistry.) |
| Databáze: | MEDLINE |
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