Microbiomes: How a gut bacterium promotes healthier living in a nematode.

Autor: MacNeil LT; Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote Institute for Infectious Disease Research, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON L8S 4L8, Canada. Electronic address: macneil@mcmaster.ca.
Jazyk: angličtina
Zdroj: Current biology : CB [Curr Biol] 2022 May 09; Vol. 32 (9), pp. R428-R430.
DOI: 10.1016/j.cub.2022.04.008
Abstrakt: A new study finds that a bacterium from the microbiome of the nematode Pristionchus pacificus can promote rapid growth, increased body size, and increased fecundity by inducing neuronal expression of TGF-β ligands. This is an intriguing example of how the microbiota induces systemic effects in the host by stimulating neuroendocrine signaling.
Competing Interests: Declaration of interests The author declares no competing interests.
(Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE