Evaluation of the variation in relative response factors of GC-MS analysis with the internal standard methods: Application for the alcoholic products quality control.

Autor: Korban A; Faculty of Science, Department of Analytical Chemistry, Charles University, Hlavova 2030/8, 128 40, Prague 2, Czech Republic; Chemistry Faculty, Department of Analytical Chemistry, Belarusian State University, Leningradskaya 14, 220050, Minsk, Belarus; Institute for Nuclear Problems of Belarusian State University, 220006, Bobruyskaya Str., 11, Minsk, Belarus. Electronic address: karbonat7@gmail.com., Čabala R; Faculty of Science, Department of Analytical Chemistry, Charles University, Hlavova 2030/8, 128 40, Prague 2, Czech Republic. Electronic address: cabala@natur.cuni.cz., Egorov V; Chemistry Faculty, Department of Analytical Chemistry, Belarusian State University, Leningradskaya 14, 220050, Minsk, Belarus. Electronic address: egorvv@bsu.by., Bosáková Z; Faculty of Science, Department of Analytical Chemistry, Charles University, Hlavova 2030/8, 128 40, Prague 2, Czech Republic. Electronic address: zuzana.bosakova@natur.cuni.cz., Charapitsa S; Institute for Nuclear Problems of Belarusian State University, 220006, Bobruyskaya Str., 11, Minsk, Belarus. Electronic address: svcharapitsa@tut.by.
Jazyk: angličtina
Zdroj: Talanta [Talanta] 2022 Aug 15; Vol. 246, pp. 123518. Date of Electronic Publication: 2022 Apr 30.
DOI: 10.1016/j.talanta.2022.123518
Abstrakt: This paper focuses on the evaluation of variation of relative response factors (RRFs) obtained by two internal standard (IS) methods that are used to control the quality of alcoholic products. A standard IS method using 1-pentanol was compared with an "Ethanol as IS" method. The variation of RRF values for both methods was determined using standard solutions based on 20, 40 and 96% ethanol-water matrices. For this purpose, solutions of the ten most abundant volatile compounds were analysed at four different concentrations (250, 500, 1000 and 5000 mg L -1 absolute alcohol, AA) within these matrices. Each solution was measured four times by gas chromatography-mass spectrometry (GC-MS) in single ion monitoring (SIM) mode under repeatability conditions. Our results showed that for the 40% and 96% matrices, the ethanol and standard IS methods showed similar relative standard deviations (RSDs) variation of no more than 2% within the 250-1000 mg L -1  AA volatile compounds concentration range. For the 20% matrix as well as for the 250-5000 mg L -1  AA concentration range the resulting variation in calibration factors reaches 10% for both methods. As for the whole range of 20-96% alcohol by volume (ABV) and 250-5000 mg L -1  AA volatile concentration range, the resultant RRFs for the standard IS method (8% RSD) were more stable than those for the ethanol IS method (almost 40% RSD). Nonlinearity of the signal-to-amount dependence was also assessed with respect to the injection and detection processes.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: