Sleep disturbances, circadian activity, and nocturnal light exposure characterize high risk for and current depression in adolescence.

Autor:	Tonon AC; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., Constantino DB; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., Amando GR; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., Abreu AC; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., Francisco AP; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., de Oliveira MAB; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., Pilz LK; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., Xavier NB; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil., Rohrsetzer F; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Souza L; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Piccin J; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Caye A; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Petresco S; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Manfro PH; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Pereira R; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Martini T; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Kohrt BA; Division of Global Mental Health, Department of Psychiatry, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA., Fisher HL; King's College London, Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.; ESRC Centre for Society and Mental Health, King's College London, London, UK., Mondelli V; King's College London, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, London, UK.; National Institute for Health Research Mental Health Biomedical Research Centre, South London and Maudsley NHS Foundation Trust and King's College London, London, UK., Kieling C; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Departament of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Division of Child & Adolescent Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Hidalgo MPL; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.; Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil.
Jazyk:	angličtina
Zdroj:	Sleep [Sleep] 2022 Jul 11; Vol. 45 (7).
DOI:	10.1093/sleep/zsac104
Abstrakt:	Study Objectives: Major depressive disorder (MDD) in adolescence is associated with irregularities in circadian rhythms and sleep. The characterization of such impairment may be critical to design effective interventions to prevent development of depression among adolescents. This study aimed to examine self-reported and actimetry-based circadian rhythms and sleep-wake behavior associated with current MDD and high risk (HR) for MDD among adolescents. Methods: Ninety-six adolescents who took part in the IDEA-RiSCo study were recruited using an empirically developed depression-risk stratification method: 26 classified as low risk (LR), 31 as HR, and 39 as a current depressive episode (MDD). We collected self-report data on insomnia, chronotype, sleep schedule, sleep hygiene as well as objective data on sleep, rest-activity, and light exposure rhythms using actimetry for 10 days. Results: Adolescents with MDD exhibited more severe insomnia, shorter sleep duration, higher social jetlag (SJL), lower relative amplitude (RA) of activity, and higher exposure to artificial light at night (ALAN) compared with the other groups. They also presented poorer sleep hygiene compared with the LR group. The HR group also showed higher insomnia, lower RA, higher exposure to ALAN, and higher SJL compared with the LR group. Conclusions: HR adolescents shared sleep and rhythm alterations with the MDD group, which may constitute early signs of depression, suggesting that preventive strategies targeting sleep should be examined in future studies. Furthermore, we highlight that actimetry-based parameters of motor activity (particularly RA) and light exposure are promising constructs to be explored as tools for assessment of depression in adolescence. (© The Author(s) 2022. Published by Oxford University Press on behalf of Sleep Research Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
Databáze:	MEDLINE
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