Automated detection of acute appendicular skeletal fractures in pediatric patients using deep learning.

Autor: Hayashi D; Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA, 02118, USA. daichi_hayashi@hotmail.com.; Department of Radiology, Stony Brook University Renaissance School of Medicine, HSc Level 4, Room 120, Stony Brook, NY, 11794, USA. daichi_hayashi@hotmail.com., Kompel AJ; Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA, 02118, USA., Ventre J; Gleamer, 117-119 Quai de Valmy, 75010, Paris, France., Ducarouge A; Gleamer, 117-119 Quai de Valmy, 75010, Paris, France., Nguyen T; Gleamer, 117-119 Quai de Valmy, 75010, Paris, France.; Service de Radiopédiatrie, Hôpital Armand-Trousseau, AP-HP, Médecine Sorbonne Université, 26 avenue du Docteur Arnold-Netter, 75012, Paris, France., Regnard NE; Gleamer, 117-119 Quai de Valmy, 75010, Paris, France.; Réseau d'Imagerie Sud Francilien, 2 avenue de Mousseau, 91000, Evry, France., Guermazi A; Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA, 02118, USA.; Department of Radiology, VA Boston Healthcare System, 1400 VFW Parkway, Suite 1B105, West Roxbury, MA, 02132, USA.
Jazyk: angličtina
Zdroj: Skeletal radiology [Skeletal Radiol] 2022 Nov; Vol. 51 (11), pp. 2129-2139. Date of Electronic Publication: 2022 May 06.
DOI: 10.1007/s00256-022-04070-0
Abstrakt: Objective: We aimed to perform an external validation of an existing commercial AI software program (BoneView™) for the detection of acute appendicular fractures in pediatric patients.
Materials and Methods: In our retrospective study, anonymized radiographic exams of extremities, with or without fractures, from pediatric patients (aged 2-21) were included. Three hundred exams (150 with fractures and 150 without fractures) were included, comprising 60 exams per body part (hand/wrist, elbow/upper arm, shoulder/clavicle, foot/ankle, leg/knee). The Ground Truth was defined by experienced radiologists. A deep learning algorithm interpreted the radiographs for fracture detection, and its diagnostic performance was compared against the Ground Truth, and receiver operating characteristic analysis was done. Statistical analyses included sensitivity per patient (the proportion of patients for whom all fractures were identified) and sensitivity per fracture (the proportion of fractures identified by the AI among all fractures), specificity per patient, and false-positive rate per patient.
Results: There were 167 boys and 133 girls with a mean age of 10.8 years. For all fractures, sensitivity per patient (average [95% confidence interval]) was 91.3% [85.6, 95.3], specificity per patient was 90.0% [84.0,94.3], sensitivity per fracture was 92.5% [87.0, 96.2], and false-positive rate per patient in patients who had no fracture was 0.11. The patient-wise area under the curve was 0.93 for all fractures. AI diagnostic performance was consistently high across all anatomical locations and different types of fractures except for avulsion fractures (sensitivity per fracture 72.7% [39.0, 94.0]).
Conclusion: The BoneView™ deep learning algorithm provides high overall diagnostic performance for appendicular fracture detection in pediatric patients.
(© 2022. The Author(s), under exclusive licence to International Skeletal Society (ISS).)
Databáze: MEDLINE
Externí odkaz: