Elevated Beta-Human Chorionic Gonadotropin in a Non-pregnant Female With Altered Kidney Function.

Autor: Ostreni I; Medicine, Touro College of Osteopathic Medicine, New York, USA., Colatosti A; Obstetrics and Gynecology, Brooklyn Hospital, Brooklyn, USA., Basile EJ; Internal Medicine, University of Florida College of Medicine, New York, USA., Rafa O; Internal Medicine, University at Buffalo, Buffalo, USA.; Medicine, Touro College of Osteopathic Medicine, New York, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2022 Apr 01; Vol. 14 (4), pp. e23747. Date of Electronic Publication: 2022 Apr 01 (Print Publication: 2022).
DOI: 10.7759/cureus.23747
Abstrakt: Elevated beta-human chorionic gonadotropin (beta-hCG) levels in postmenopausal women is a finding known in the literature; however, it still commonly leads to unnecessary and extensive diagnostic workup. We present the case of a 48-year-old African-American postmenopausal female with acute kidney injury on chronic kidney disease (CKD) stage 5 and an incidental finding of elevated serum beta-hCG. Abdominal and transvaginal ultrasound showed no evidence of intrauterine or ectopic pregnancy or gestational trophoblastic disease. Menopausal status was confirmed with follicle-stimulating hormone (FSH) measurement, and following the improvement of renal status, beta-hCG levels were normalized to expected values for the patient's age group. The etiology of elevated beta-hCG was suspected to be from the pituitary as previous literature has shown decreasing beta-hCG levels in postmenopausal women following the administration of gonadotropin-releasing hormone (GnRH) antagonist.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Ostreni et al.)
Databáze: MEDLINE