Pharmacological and natural products diversity of the brown algae genus Sargassum .

Autor: Rushdi MI; Department of Pharmacognosy, Faculty of Pharmacy, South Valley University 83523 Qena Egypt., Abdel-Rahman IAM; Department of Pharmacognosy, Faculty of Pharmacy, South Valley University 83523 Qena Egypt., Saber H; Department of Botany and Microbiology, Faculty of Science, South Valley University 83523 Qena Egypt., Attia EZ; Department of Pharmacognosy, Faculty of Pharmacy, Minia University 61519 Minia Egypt usama.ramadan@mu.edu.eg +20-86-2369075 +20-86-2347759., Abdelraheem WM; Department of Medical Microbiology and Immunology, Faculty of Medicine, Minia University 61519 Minia Egypt., Madkour HA; Department of Marine and Environmental Geology, National Institute of Oceanography and Fisheries Red Sea Branch 84511 Hurghada Egypt., Hassan HM; Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University Beni-Suef 62514 Egypt., Elmaidomy AH; Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University Beni-Suef 62514 Egypt., Abdelmohsen UR; Department of Pharmacognosy, Faculty of Pharmacy, Minia University 61519 Minia Egypt usama.ramadan@mu.edu.eg +20-86-2369075 +20-86-2347759.; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University Universities Zone 61111 New Minia City Egypt.
Jazyk: angličtina
Zdroj: RSC advances [RSC Adv] 2020 Jul 01; Vol. 10 (42), pp. 24951-24972. Date of Electronic Publication: 2020 Jul 01 (Print Publication: 2020).
DOI: 10.1039/d0ra03576a
Abstrakt: Sargassum (F. Sargassaceae) is an important seaweed excessively distributed in tropical and subtropical regions. Different species of Sargassum have folk applications in human nutrition and are considered a rich source of vitamins, carotenoids, proteins, and minerals. Many bioactive compounds chemically classified as terpenoids, sterols, sulfated polysaccharides, polyphenols, sargaquinoic acids, sargachromenol, and pheophytin were isolated from different Sargassum species. These isolated compounds and/or extracts exhibit diverse biological activities, including analgesic, anti-inflammatory, antioxidant, neuroprotective, anti-microbial, anti-tumor, fibrinolytic, immune-modulatory, anti-coagulant, hepatoprotective, and anti-viral activities. This review covers the literature from 1974 to 2020 on the genus Sargassum , and reveal the active components together with their biological activities according to their structure to create a base for additional studies on the clinical applications of Sargassum .
Competing Interests: The authors declare there were no conflicts of interest.
(This journal is © The Royal Society of Chemistry.)
Databáze: MEDLINE